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4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Influence of time of rejection on long-term graft survival in renal transplantation.
Gerhard Opelz,Bernd Döhler +1 more
TL;DR: The time point of occurrence and the degree of functional recovery after rejection treatment were found to significantly influence the impact of ARE on long-term graft survival, and the associated risks were able to be quantify.
Journal ArticleDOI
Assessment of Delay in Age-appropriate Vaccination Using Survival Analysis
Gustavo H. Dayan,Kate M. Shaw,Andrew L. Baughman,Liliana Orellana,Raúl Forlenza,Alejandro Ellis,Jorge Chaui,Silvia Kaplan,Peter M. Strebel +8 more
TL;DR: Survival analysis methods were helpful in measuring vaccine uptake and should be considered in future surveys when assessing delay in age-appropriate vaccination.
Journal Article
Body Size and Composition and Prostate Cancer Risk
TL;DR: This work found no overall association between prostate cancer and any anthropometric measurement, and stratified by cancer aggressiveness revealed modest associations between measures of adiposity and the risk of aggressive disease.
Journal ArticleDOI
Pilot study to determine the impact of a multidisciplinary educational intervention in patients hospitalized with heart failure.
Femida Gwadry-Sridhar,Femida Gwadry-Sridhar,J. Malcolm O. Arnold,Ying Zhang,James E. Brown,Gordon Marchiori,Gordon H. Guyatt +6 more
TL;DR: An inhospital educational intervention improved knowledge and, possibly, quality of life and may be useful as part of a comprehensive compliance enhancing strategy in patients with HF.
Journal ArticleDOI
The prognostic significance of CDKN2A, CDKN2B and MTAP inactivation in B-lineage acute lymphoblastic leukemia of childhood. Results of the EORTC studies 58881 and 58951.
Delphine Mirebeau,Cécile Acquaviva,Stefan Suciu,Raphaëlle Bertin,Nicole Dastugue,Alain Robert,Patrick Boutard,Francoise Mechinaud,Emmanuel Plouvier,Jacques Otten,Etienne Vilmer,Hélène Cavé,Eortc-Clg +12 more
TL;DR: Although CDKN2A inactivation was more often associated with poor prognostic features in B-lineage ALL, it failed to influence the outcome of the patients significantly, and did not influence the 6-year event-free survival rate either.