Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Dissertation
Méthodes d’analyse de survie, valeurs manquantes et fractions attribuables temps dépendantes : application aux décès par cancer de la prostate
TL;DR: In this article, the authors propose a formulation of the regles de Rubin apres transformation log-log complementaire for combiner les estimations de survie, in order to determine the cause of deces.
Journal ArticleDOI
Modeling Grouped Survival Data with Time-Dependent Covariates
TL;DR: In this paper, proportional hazards and logistic models for grouped survival data were extended to incorporate time-dependent covariates, motivated by a forestry experiment designed to compare five different water stresses in Eucalyptus grandis seedlings.
Journal ArticleDOI
A cure rate survival model under a hybrid latent activation scheme
TL;DR: A method of estimating the numerical characteristics of unobservable stages (such as initiation, promotion and progression) of carcinogenesis from data on tumor size at detection in the presence of latent competing causes is proposed.
Dissertation
Using administrative linked datasets to explain differences in child mortality between England and Sweden
TL;DR: The biggest reductions in child mortality in England relative to Sweden could be achieved by reducing the prevalence of adverse birth characteristics, as well as reducing socio-economic disadvantage before and during pregnancy.
Dissertation
Epidemiology of health and performance in New Zealand racehorses : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Epidemiology at Massey University, Palmerston North, New Zealand
TL;DR: In this article, the authors describe training and racing patterns, and causes of wastage in New Zealand Thoroughbred racehorses, and two separate studies were performed, one involved analysis of data from before and after construction of a new training track at the Matamata Racing Club and the second involved a longitudinal study over a 34-month period, and that involved 1,571 horses.