Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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Risk factors for scald injury in children under 5 years of age: A case-control study using routinely collected data
TL;DR: Male gender, age, age (2 years), higher birth order, single-parent families and increasing index of material deprivation were associated with increased odds of scald injury and older maternal age at childbirth was associated with decreased odds ofScald injury.
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Parametric and penalized generalized survival models
TL;DR: Applying these models to three cancer survival datasets, it is found that the proportional odds model is better than the proportional hazards model for two of the datasets.
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A game-theoretic incentive scheme for social-aware routing in selfish mobile social networks
TL;DR: A bargaining-based incentive scheme to stimulate selfish nodes in cooperation, namely GISSO, to stimulate SS nodes in message relaying and guarantee that the routing performance gets maximized when SS nodes follow the scheme is proposed.
Journal ArticleDOI
Effects of Plant Identity and Chemical Constituents on the Efficacy of a Baculovirus Against Heliothis Virescens
Kelli Hoover,Julie L. Yee,Christine M. Schultz,David M. Rocke,Bruce D. Hammock,Sean S. Duffey +5 more
TL;DR: The levels of phenolic substrates and two foliar oxidative enzymes, peroxidase and polyphenol oxidase, were significant predictors of disease caused by a baculovirus in Heliothis virescens fed on either cotton or lettuce.
Journal ArticleDOI
Neural Network Models for Breast Cancer Prognosis
TL;DR: Various ways of using neural network models to extend traditional statistical models in this situation are investigated, finding that such models are better able to model both non-linear effects of prognostic factors and interactions between them, than linear logistic or Cox regression models.
References
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Journal ArticleDOI
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
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Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.