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4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Mucosal Melanomas of the Head and Neck: The Role of Postoperative Radiation Therapy
Kunal Saigal,Donald T. Weed,Isildinha M. Reis,Arnold M. Markoe,Arnold M. Markoe,Aaron H. Wolfson,Aaron H. Wolfson,Janet Nguyen-Sperry +7 more
TL;DR: Patients with mucosal melanoma of the head and neck are best treated with surgery to achieve negative margins, followed by postoperative RT to optimize local control, as regional failures were not predominant.
Journal ArticleDOI
Sources of Safety Data and Statistical Strategies for Design and Analysis: Clinical Trials
TL;DR: Clinical trials are an important source of safety data that contribute to the totality of safety information available to generate evidence for regulators, sponsors, payers, physicians, and patients.
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Predictors of a favorable outcome in patients treated by chiropractors for neck pain (vol 33, pg 1451, 2008)
TL;DR: In this paper, the authors examined which clinical and sociodemographic baseline variables can predict a favorable outcome in subjects with neck pain treated by chiropractors, and found that shorter duration of neck pain at the first visit was the only predictor consistently found to be predictive of favorable outcome for all three outcome measures examined.
Journal ArticleDOI
Suicide by self-burning in Iraqi Kurdistan: description and risk factors.
TL;DR: Suicide by self-burning is common in Iraqi Kurdistan especially among women and urgent action is required to provide a better understanding of the situation, and identify partners, capacities, and opportunities for action.
Journal ArticleDOI
Spontaneous closure of atrial septal defects in premature vs. full-term neonates
TL;DR: It is concluded that the majority of neonatal ASDs will close, with EGA and PDA acting as important influences on closure.