Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Journal ArticleDOI
Exploratory Analysis of Time from HIV Diagnosis to ART Start, Factors and effect on survival: A longitudinal follow up study at seven teaching hospitals in Ethiopia.
Alula M. Teklu,Kesetebirhan Delele,Mulu Abraha,Bekele Belayhun,Esayas Kebede Gudina,Abiy Nega +5 more
TL;DR: Time to enrollment and duration of ART eligibility assessment as well as ART initiation time after eligibility is improving and further study is required to identify why mortality is slightly increasing after 2010.
Journal ArticleDOI
The Breslow estimator of the nonparametric baseline survivor function in Cox's regression model: some heuristics.
TL;DR: A heuristic representation is brought out that may help to de-mystify the structure of the components of the nonparametric baseline survivor function in Cox's life table regression model.
Journal ArticleDOI
An oral preparation of Lactobacillus acidophilus for the treatment of uncomplicated acute watery diarrhoea in Vietnamese children: study protocol for a multicentre, randomised, placebo-controlled trial
Marion-Eliëtte Kolader,Ha Vinh,Pham Thi Ngoc Tuyet,Corinne N. Thompson,Marcel Wolbers,Laura Merson,James Campbell,Tran Thi Ngoc Dung,Ha Manh Tuan,Nguyen Van Vinh Chau,Jeremy Farrar,H. Rogier van Doorn,Stephen Baker,Stephen Baker +13 more
TL;DR: Whether probiotics are beneficial as an adjuvant treatment for children with acute watery diarrhoea in Vietnam is investigated, with the aim of guiding clinical practice through improved regional evidence.
Dissertation
Causal modelling of survival data with informative noncompliance
TL;DR: The present work applies a principal stratification method to data from the Esprit trials study to ascertain whether or not unopposed oestrogen (hormone replacement therapy-HRT) reduced the risk of further cardiac events in postmenopausal women who survive a first myocardial infarction.
Journal ArticleDOI
Patients who restart antiretroviral medication after interruption remain at high risk of unfavorable outcomes in Ethiopia
TL;DR: Treatment interruption patterns over time among clients who interrupt and subsequently resume HAART, and those who are continuously engaged in treatment, are described and clinical factors associated with loss to engagement are determined.