Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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Human Papillomavirus Infection in Women Infected with the Human Immunodeficiency Virus
Xiao-Wei Sun,Louise Kuhn,Tedd V. Ellerbrock,Mary Ann Chiasson,Timothy J. Bush,Thomas C. Wright +5 more
TL;DR: HIV-seropositive women have a high rate of persistent HPV infections with the types of HPV that are strongly associated with the development of high-grade squamous intraepithelial lesions and invasive cervical cancer.
Journal ArticleDOI
Policing the Bargain: Coalition Government and Parliamentary Scrutiny
Lanny W. Martin,Georg Vanberg +1 more
TL;DR: In this paper, the authors argue that parties will make use of parliamentary scrutiny of "hostile" ministerial proposals to overcome the potential problems of delegation and enforce the coalition bargain, and their analysis of original data on government bills in Germany and the Netherlands supports this argument.
Journal ArticleDOI
Prognostic Impact of the Indexation of Left Ventricular Mass in Patients Undergoing Dialysis
Carmine Zoccali,Francesco A. Benedetto,Francesca Mallamaci,Giovanni Tripepi,Giuseppe Giacone,Alessandro Cataliotti,Giuseppe Seminara,Benedetta Stancanelli,Lorenzo Malatino +8 more
TL;DR: The indexing of LVM by height(2.7) provides more powerful prediction of mortality and cardiovascular outcomes than the BSA-based method, and the use of this index appears to be appropriate in patients undergoing dialysis.
Journal ArticleDOI
Breast-Conserving Treatment With or Without Radiotherapy in Ductal Carcinoma In Situ: 15-Year Recurrence Rates and Outcome After a Recurrence, From the EORTC 10853 Randomized Phase III Trial
Mila Donker,Saskia Litière,G. Werutsky,Jean-Pierre Julien,Ian S. Fentiman,Roberto Agresti,P. Rouanet,Christine Tunon de Lara,Harry Bartelink,Nicole Duez,Emiel J. Th. Rutgers,Nina Bijker +11 more
TL;DR: At 15 years, almost one in three nonirradiated women developed an LR after LE for DCIS, and RT reduced this risk by a factor of 2, although women who developed an invasive recurrence had worse survival.
Journal ArticleDOI
Role of N-terminal brain natriuretic peptide (N-TproBNP) in scleroderma-associated pulmonary arterial hypertension
MH Williams,Clive Handler,Raza Akram,CJ Smith,Clare Das,Joanna Smee,Devaki Nair,Christopher P. Denton,Carol M. Black,John G Coghlan +9 more
TL;DR: Raised N-TproBNP levels are directly related to the severity of PAH and are associated with a greater than three-fold increase in mortality, and may indicate therapeutic failure.
References
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Journal ArticleDOI
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.