Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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Contribution of vascular endothelial growth factor to the Nottingham prognostic index in node-negative breast cancer.
Danila Coradini,Patrizia Boracchi,M. Grazia Daidone,C. Pellizzaro,Patrizia Miodini,M Ammatuna,Gorana Tomasic,Elia Biganzoli +7 more
TL;DR: The prognostic contribution of intratumour VEGF, the most important factor in tumour-induced angiogenesis, to NPI was evaluated by using flexible modelling in a series of 226 N-primary breast cancer patients in which steroid receptors and cell proliferation were also accounted for.
Journal ArticleDOI
21-Gene Recurrence Score Assay Predicts Benefit of Post-Mastectomy Radiotherapy in T1-2 N1 Breast Cancer.
Chelain R. Goodman,Brandon Luke L. Seagle,Masha Kocherginsky,Eric D. Donnelly,Shohreh Shahabi,Jonathan B. Strauss +5 more
TL;DR: Post-mastectomy radiotherapy (PMRT) yields improvements in both locoregional control and overall survival and may confer the greatest OS benefit for patients at the lowest risk of distant recurrence, according to the results of an observational cohort study.
Journal ArticleDOI
Status epilepticus without an underlying cause and risk of death: a population-based study.
TL;DR: In this paper, the independent effect of status epilepticus (SE) on risk of death was determined by studying idiopathic/cryptogenic status epilepsy (SE), and the adjusted relative risk for death in those with SE was 2.4 (95% confidence interval [CI], 0.9-6.3) over 10 years.
Journal ArticleDOI
Identifying COPD patients at increased risk of mortality: Predictive value of clinical study baseline data *
TL;DR: Health status measured by S GRQ and SF-36 may be important for predicting COPD patients at increased mortality risk, with SGRQ total score emerging as the strongest predictor compared with other baseline covariates.
Journal ArticleDOI
Correlates to survival of juvenile sea otters in Prince William Sound, Alaska, 1992-1993
TL;DR: Sea otters from EPWS were in better condition (mass/length) than WPWS sea otters, consistent with either an effect of length of occupation or the effects of oil on the prey base or a combination of these effects.
References
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Journal ArticleDOI
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.