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4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Human T-Lymphotropic Virus Type-I Infection, Antibody Titers and Cause-specific Mortality among Atomic-bomb Survivors
Kokichi Arisawa,Midori Soda,Masazumi Akahoshi,Tatsuki Matsuo,Eiji Nakashima,Masao Tomonaga,Hiroshi Saito +6 more
TL;DR: Findings may support the idea that HTLV‐I infection exerts adverse effects on mortality from causes other than adult T‐cell leukemia/lymphoma, and further studies on confounding by HCV/HBV infections and the interaction between HCV-HBV and HTLV-I may be required to analyze the increased mortality from liver cancer and chronic liver diseases.
Journal Article
Factors affecting days open in Holstein dairy cattle in Khorasan Razavi province, Iran; a cox proportional hazard model.
TL;DR: Quantifying the effect of disease on reproductive performance provides a means for ranking disorders in terms of their effect on fertility, allowing intervention strategies designed to optimise herd health and production to be further refined.
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Exploratory analysis on the use of statins with or without n-3 PUFA and major events in patients discharged for acute myocardial infarction: an observational retrospective study.
TL;DR: Among a representative sample of patients discharged with MI in Italy, clinically significant synergism between the effects of statins and n-3 PUFA for most cardiovascular outcomes, including all cause mortality is observed.
Improving workforce retention: Developing an integrated logic model to maximise sustainability of small rural and remote health care services
John Stirling Humphreys,John Wakerman,Pim Kuipers,Deborah Russell,Shari Siegloff,Kerry Homer,Robert Wells +6 more
TL;DR: This landmark study represents the first time health workforce retention benchmarks and recruitment costs have been identified for rural and remote primary health care services located in different geographical contexts and has identified sentinel indicators which will enable health services and health authorities to better use their human resource data to monitor workforce performance and plan future retention measures designed to maximise length of service.
Journal ArticleDOI
The influence of meal size on prey DNA detectability in piscivorous birds.
TL;DR: A feeding trial on abundant piscivorous birds, Great Cormorants, is presented to assess meal size effects on postfeeding prey DNA detection success and the importance of large numbers of dietary samples to obtain reliable trophic data.