Journal ArticleDOI
Plagiochin E, an antifungal active macrocyclic bis(bibenzyl), induced apoptosis in Candida albicans through a metacaspase-dependent apoptotic pathway
Reads0
Chats0
TLDR
It is reported for the first time that PLE induced apoptosis in C. albicans through a metacaspase-dependent apoptotic pathway, indicating the ROS was an important mediator of PLE-induced apoptosis.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 2010-04-01. It has received 113 citations till now. The article focuses on the topics: Phosphatidylserine & Apoptosis.read more
Citations
More filters
Journal ArticleDOI
Silver nanoparticles induce apoptotic cell death in Candida albicans through the increase of hydroxyl radicals.
TL;DR: The results indicate that silver nanoparticles possess antifungal effects with apoptotic features and suggest that the hydroxyl radicals generated bysilver nanoparticles have a significant role in mitochondrial dysfunctional apoptosis.
Journal ArticleDOI
Phytochemical and biological studies of bryophytes.
TL;DR: Each liverwort biosynthesizes unique components, which are valuable for their chemotaxonomic classification, and typical chemical structures and biological activity of the selected liverworts constituents as well as the total synthesis of some biologically active compounds are summarized.
Journal ArticleDOI
Reactive oxygen species-inducing antifungal agents and their activity against fungal biofilms
TL;DR: This review provides an overview of the different classes of antimycotics and novel antifungal compounds that induce ROS in fungal planktonic and biofilm cells and different strategies to further enhance the antibiofilm activity of such ROS-inducing antimyCotics will be discussed.
Journal ArticleDOI
Guidelines and recommendations on yeast cell death nomenclature
Didac Carmona-Gutierrez,Maria A. Bauer,Andreas Zimmermann,Andrés Aguilera,Nicanor Austriaco,Kathryn R. Ayscough,Rena Balzan,Shoshana Bar-Nun,Antonio Barrientos,Peter Belenky,Marc Blondel,Ralf J. Braun,Michael Breitenbach,William Wc Burhans,Sabrina Büttner,Sabrina Büttner,Duccio Cavalieri,Michael Chang,Katrina Kf Cooper,Manuela Côrte-Real,Vítor Costa,Vítor Costa,Christophe Cullin,Ian W. Dawes,Jörn Dengjel,Martin Mb Dickman,Tobias Eisenberg,Birthe Fahrenkrog,Nicolas Fasel,Kai-Uwe Fröhlich,Ali Gargouri,Sergio Giannattasio,Paola Goffrini,Campbell W. Gourlay,Chris M. Grant,Michael Mt Greenwood,Nicoletta Guaragnella,Thomas Heger,Jürgen J. Heinisch,Eva Herker,Johannes M. Herrmann,Sebastian J. Hofer,Antonio Jiménez-Ruiz,Helmut Jungwirth,Katharina Kainz,Dimitrios P. Kontoyiannis,Paula Ludovico,Paula Ludovico,Stéphen Manon,Enzo Martegani,Cristina Mazzoni,Lynn La Megeney,Lynn La Megeney,Christa Meisinger,Jens Nielsen,Jens Nielsen,Thomas Nyström,Heinz Hd Osiewacz,Tiago Tf Outeiro,Hay-Oak Park,Tobias Pendl,Dina Petranovic,Stéphane Picot,Peter Polčic,Ted Powers,Mark Ramsdale,Mark Rinnerthaler,Patrick Rockenfeller,Patrick Rockenfeller,Christoph Ruckenstuhl,Raffael Schaffrath,María Segovia,Fedor Ff Severin,Amir Sharon,Stephan J. Sigrist,Cornelia Sommer-Ruck,Maria João Sousa,Johan Jm Thevelein,Karin Thevissen,Vladimir I. Titorenko,Michel Mb Toledano,Mick F. Tuite,F-Nora Vögtle,Benedikt Westermann,Joris Winderickx,Silke Wissing,Stefan Wölfl,Zhaojie J Zhang,Richard Y. Zhao,Bing Zhou,Lorenzo Galluzzi,Lorenzo Galluzzi,Guido Kroemer,Frank Madeo +93 more
TL;DR: Unified criteria for the definition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria are proposed.
Journal ArticleDOI
Caspofungin Kills Candida albicans by Causing both Cellular Apoptosis and Necrosis
TL;DR: Caspofungin exerts activity against C. albicans by directly killing cells (resulting in necrosis) and causing others to undergo programmed cell death (apoptosis).
References
More filters
Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V.
TL;DR: The Annexin V assay offers the possibility of detecting early phases of apoptosis before the loss of cell membrane integrity and permits measurements of the kinetics of apoptotic death in relation to the cell cycle.
Journal ArticleDOI
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.
Seamus J. Martin,Chris P. M. Reutelingsperger,A J McGahon,J. A. Rader,R. C. A. A. Van Schie,Drake LaFace,Douglas R. Green +6 more
TL;DR: It is shown that PS externalization is an early and widespread event during apoptosis of a variety of murine and human cell types, regardless of the initiating stimulus, and precedes several other events normally associated with this mode of cell death.
Journal ArticleDOI
Mitochondria as the central control point of apoptosis
TL;DR: The current view of the mechanisms that lead to the efflux of many proteins from mitochondria during apoptosis and the role played by Bcl-2 family proteins in the control of this event are summarized.
Journal ArticleDOI
Annexin V-affinity assay: a review on an apoptosis detection system based on phosphatidylserine exposure.
Manon van Engeland,Luc J. W. Nieland,Frans C. S. Ramaekers,Bert Schutte,Chris P. M. Reutelingsperger +4 more
TL;DR: The basic mechanisms underlying the loss of membrane asymmetry during apoptosis are described and the novel annexin V-binding assay is discussed, an extension to the current available methods.