C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Patent
FHIT proteins and nucleic acids and methods based thereon
TL;DR: The use of FHIT genes and their encoded proteins as diagnostic and therapeutic reagents for the detection and treatment of disease states associated with cell overproliferation is discussed in this paper.
Journal ArticleDOI
HIF-1α promotes autophagic proteolysis of Dicer and enhances tumor metastasis
Hui Huang Lai,Jie Ning Li,Ming-Yang Wang,Hsin-Yi Huang,Carlo M. Croce,Hui-Lung Sun,Yu Jhen Lyu,Jui-Wen Kang,Ching Feng Chiu,Mien Chie Hung,Hiroshi I. Suzuki,Pai Sheng Chen +11 more
TL;DR: This study uncovered a connection between oncogenic HIF-1&agr; and the tumor-suppressive Dicer, which is transcription independent and occurs through previously unrecognized protein interaction–mediated ubiquitination and autophagic proteolysis.
Patent
Methods for differentiating pancreatic cancer from normal pancreatic function and/or chronic pancreatitis
TL;DR: In this article, methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer, along with methods of identifying anti-pancreatic cancer agents are provided.
Journal ArticleDOI
miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells.
Zaidoun Salah,Zaidoun Salah,Rand Arafeh,Vadim Maximov,Marco Galasso,Saleh Khawaled,Samah Abou-Sharieha,Stefano Volinia,Stefano Volinia,Kevin B. Jones,Carlo M. Croce,Rami I. Aqeilan,Rami I. Aqeilan +12 more
TL;DR: It is established that miR-27a/miR- 27a* pair plays a significant role in OS metastasis and proposes it as a potential diagnostic and therapeutic target in managing OS metastases.
Journal ArticleDOI
Micro-RNAs in gastrointestinal and liver disease.
TL;DR: This review discusses the most important advances in the development of small, noncoding RNAs and their role in regulating almost every cellular process.