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Carlo M. Croce

Researcher at Ohio State University

Publications -  1156
Citations -  199822

Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.

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miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation.

TL;DR: It is reported that miR-221&222 are overexpressed in aggressive non-small cell lung cancer and hepatocarcinoma cells, as compared with less invasive and/or normal lung and liver cells, and it is demonstrated that the MET oncogene is involved in miR+222 activation through the c-Jun transcription factor.
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MicroRNA Expression Abnormalities in Pancreatic Endocrine and Acinar Tumors Are Associated With Distinctive Pathologic Features and Clinical Behavior

TL;DR: Results suggest that alteration in microRNA expression is related to endocrine and acinar neoplastic transformation and progression of malignancy, and might prove useful in distinguishing tumors with different clinical behavior.
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MicroRNA Expression, Survival, and Response to Interferon in Liver Cancer

TL;DR: The expression patterns of microRNAs in liver tissue differ between men and women with hepatocellular carcinoma, and the miR-26 expression status of such patients is associated with survival and response to adjuvant therapy with interferon alfa.
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MicroRNA expression and function in cancer

TL;DR: Large high-throughput studies in patients revealed that miRNA profiling have the potential to classify tumors with high accuracy and predict outcome and the role of miRNAs in the pathogenesis of cancer is examined.