C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Interferon modulation of cellular microRNAs as an antiviral mechanism.
Irene M. Pedersen,Guofeng Cheng,Stefan Wieland,Stefano Volinia,Carlo M. Croce,Francis V. Chisari,Michael David +6 more
TL;DR: These findings strongly support the notion that mammalian organisms too, through the interferon system, use cellular miRNAs to combat viral infections.
Journal ArticleDOI
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
Y. Gu,Tomonori Nakamura,Hansjuerg Alder,R Prasad,O. Canaani,G. Cimino,Carlo M. Croce,Eli Canaani +7 more
TL;DR: The t(4;11) chromosome translocation results in two reciprocal fusion products coding for chimeric proteins derived from ALL-1 and from a gene on chromosome 4, which suggests that each 11q23 abnormality gives rise to a specific oncogenic fusion protein.
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E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer
Fabio Petrocca,Fabio Petrocca,Rosa Visone,Mariadele Rapazzotti Onelli,Manisha H. Shah,Milena S. Nicoloso,Ivana de Martino,Dimitrios Iliopoulos,Emanuela Pilozzi,Chang Gong Liu,Massimo Negrini,Luigi Cavazzini,Stefano Volinia,Stefano Volinia,Hansjuerg Alder,Luigi P. Ruco,Gustavo Baldassarre,Carlo M. Croce,Andrea Vecchione,Andrea Vecchione +19 more
TL;DR: In this article, the miR-106b-25 cluster, upregulated in a subset of human gastric tumors, is activated by E2F1 in parallel with its host gene, Mcm7.
Journal ArticleDOI
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
Nadia Felli,Laura Fontana,Elvira Pelosi,Rosanna Botta,Désirée Bonci,Francesco Facchiano,Francesca Liuzzi,Valentine Lulli,Ornella Morsilli,Simona Santoro,Mauro Valtieri,Mauro Valtieri,George A. Calin,Chang Gong Liu,Antonio Sorrentino,Antonio Sorrentino,Carlo M. Croce,Cesare Peschle,Cesare Peschle +18 more
TL;DR: It is indicated that the decline of miR 221 and 222 during exponential E growth unblocks kit protein production at mRNA level, thus leading to expansion of early erythroblasts, and the results on kit+ erythroleukemic cells suggest a potential role of these miRs in cancer therapy.
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Cyclin G1 Is a Target of miR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma
Laura Gramantieri,Manuela Ferracin,Francesca Fornari,Angelo Veronese,Silvia Sabbioni,Chang Gong Liu,George A. Calin,Catia Giovannini,Eros Ferrazzi,Gian Luca Grazi,Carlo M. Croce,Carlo M. Croce,Luigi Bolondi,Massimo Negrini,Massimo Negrini +14 more
TL;DR: Results indicate that cyclin G1 is a target of miR-122a and expand the knowledge of the molecular alterations involved in HCC pathogenesis and of the role of miRNAs in human cancer.