C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Regulation of acute graft-versus-host disease by microRNA-155
Parvathi Ranganathan,Catherine E. A. Heaphy,Stefan Costinean,Nicole Stauffer,Caroline Na,Mehdi Hamadani,Ramasamy Santhanam,Charlene Mao,Patricia A. Taylor,Sukhinder K. Sandhu,Gang He,Arwa Shana'ah,Gerard J. Nuovo,Alessandro Laganà,Luciano Cascione,Luciano Cascione,Susanna Obad,Oliver Broom,Sakari Kauppinen,Sakari Kauppinen,John C. Byrd,Michael A. Caligiuri,Danilo Perrotti,Gregg A. Hadley,Guido Marcucci,Steven M. Devine,Bruce R. Blazar,Carlo M. Croce,Ramiro Garzon +28 more
TL;DR: It is shown that miR-155 expression was up-regulated in T cells from mice developing aGVHD after alloHSCT, and this data indicate a role for microRNA-155 in the regulation of GVHD and point to mi R-155 as a novel target for therapeutic intervention in this disease.
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Association of SV40 with human tumors
TL;DR: Before accepting the possibility that SV40 was present in human tumors, a multi-laboratory study needed to be conducted, and evidence in favor and against a possible association of SV40 with human cancer was reviewed at an international concensus meeting at the University of Chicago on 20, 21 April 2001.
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Familial cancer associated with a polymorphism in ARLTS1.
George A. Calin,Francesco Trapasso,Masayoshi Shimizu,Calin Dan Dumitru,Sai Yendamuri,Andrew K. Godwin,Manuela Ferracin,Guido Bernardi,Devjani Chatterjee,Gustavo Baldassarre,Shashi Rattan,Hansjuerg Alder,Hideaki Mabuchi,Takeshi Shiraishi,Lise Lotte Hansen,Jens Overgaard,Vlad Herlea,Francesca Romana Mauro,Guillaume Dighiero,Benjamin Movsas,Laura Z. Rassenti,Thomas J. Kipps,Raffaele Baffa,Alfredo Fusco,Masaki Mori,Giandomenico Russo,Chang Gong Liu,Donna Neuberg,Florencia Bullrich,Massimo Negrini,Massimo Negrini,Carlo M. Croce,Carlo M. Croce +32 more
TL;DR: A genetic variant of ARLTS1 predisposes patients to familial cancer, a member of the ADP-ribosylation factor family, with properties of a tumor-suppressor gene.
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A new role for microRNAs, as ligands of Toll-like receptors.
TL;DR: It is discovered that miRNAs released by cancer cells within microvesicles can reach and bind to Toll-like receptors in surrounding immune cells, and activate them in a paracrine loop, which provides the rationale for the development of new drugs that might be used in the treatment of cancer as well as other inflammation-related diseases.
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Sequence of the FRA3B common fragile region: Implications for the mechanism of FHIT deletion
Hiroshi Inoue,Hideshi Ishii,Hansjuerg Alder,Eric L. Snyder,Teresa Druck,Kay Huebner,Carlo M. Croce +6 more
TL;DR: Sequence analysis of 276 kb of the FRA3B/FHIT locus and 22 associated cancer cell deletion endpoints shows that this locus is a frequent target of homologous recombination between long interspersed nuclear element sequences resulting in FHIT gene internal deletions, probably as a result of carcinogen-induced damage at F RA3B fragile sites.