C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Discovery and functional implications of a miR-29b-1/miR-29a cluster polymorphism in acute myeloid leukemia
Apollinaire Ngankeu,Parvathi Ranganathan,Violaine Havelange,Deedra Nicolet,Deedra Nicolet,Stefano Volinia,Bayard L. Powell,Jonathan E. Kolitz,Geoffrey L. Uy,Richard Stone,Steven M. Kornblau,Michael Andreeff,Carlo M. Croce,Clara D. Bloomfield,Ramiro Garzon +14 more
TL;DR: A significant enrichment for the presence of the miR-29 polymorphism in core binding factor (CBF) newly diagnosed AML patients is found and it is shown that this polymorphism negatively impacts the ability of mi R-29b-1/miR- 29a cluster to target MCL-1 and CDK6, both known miR -29 targets.
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Preclinical Assessment of FHIT Gene Replacement Therapy in Human Leukemia Using a Chimeric Adenovirus, Ad5/F35
Flavia Pichiorri,Francesco Trapasso,Tiziana Palumbo,Rami I. Aqeilan,Alessandra Drusco,Bradley W. Blaser,Dimitrios Iliopoulos,Michael A. Caligiuri,Kay Huebner,Carlo M. Croce +9 more
TL;DR: A chimeric FHIT-containing adenovirus composed of Ad5 and the group B adenvirus called F35 is generated with which it is able to efficiently infect hematopoietic cells and induces both antiproliferative and proapoptotic effects involving the intrinsic caspase apoptotic pathway.
Journal ArticleDOI
Genetics: Are circRNAs involved in cancer pathogenesis?
TL;DR: The experimental approach used was inadequate to generate sufficient evidence to prove that circular RNAs derived from cancer-associated chromosomal translocations have an oncogenic role, calling the study into question.
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High-mobility-group A1 (HMGA1) proteins down-regulate the expression of the recombination activating gene 2 (RAG2)
Sabrina Battista,Monica Fedele,Josefina Martinez Hoyos,Francesca Pentimalli,Giovanna Maria Pierantoni,Rosa Visone,Ivana De Martino,Carlo M. Croce,Alfredo Fusco +8 more
TL;DR: It is shown that RAG2 gene expression is up-regulated in Hmga1-/- ES (embryonic stem) cells and EBs as well as in yolk sacs and fibroblasts from Hmgo-/- mice, suggesting that HMGA1 proteins control RAG1 gene expression both in vitro and in vivo.
Journal Article
Seven megabase yeast artificial chromosome contig at region 11p15: identification of a yeast artificial chromosome spanning the breakpoint of a chromosomal translocation found in a case of Beckwith-Wiedemann syndrome.
Massimo Negrini,Silvia Sabbioni,Masataka Ohta,Maria Luisa Veronese,Shashi Rattan,Claudine Junien,Carlo M. Croce +6 more
TL;DR: A yeast artificial chromosome contig is developed that covers up to 7 Mb of chromosome region 11p15 and 18 new STS markers, which have been located in the contig in relation to 16 known markers, are developed.