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Carlo M. Croce

Researcher at Ohio State University

Publications -  1156
Citations -  199822

Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.

Papers
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Journal ArticleDOI

miRNA clusters as therapeutic targets for hormone-resistant breast cancer

TL;DR: The role of microRNAs in breast cancer and Estrogen Receptor alpha signaling is broadly summarized and key miRNAs involved in tamoxifen, fulvestrant, and aromatase inhibitor resistance are discussed.
Patent

Materials and methods useful for affecting tumor cell growth, migration and invasion

TL;DR: In this paper, it is disclosed that miR-221 and miR -222 down-regulate PTEN and TIMP3 tumor suppressors, resulting in TRAIL resistance.
Journal ArticleDOI

Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains

TL;DR: Zn supplementation significantly reduced tumor burdens in mice with multiple tumor suppressor deficiencies, and Histological analysis of forestomach tissues showed significant decreases in severity of preneoplastic and neoplastic lesions in Zn-supplemented cohorts of each mouse strain.
Journal Article

Detection of minimal residual disease in leukemic patients with the t(10;14)(q24;q11) chromosomal translocation.

TL;DR: Application of the polymerase chain reaction technology in amplification of the t(10;14)(q24;q11) chromosomal juncture during clinical remission permitted us to increase the detection level of neoplastic cells up to 1 leukemic cell/125,000 normal cells using 1 microgram of DNA.