C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
Papers
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Journal ArticleDOI
miRNA clusters as therapeutic targets for hormone-resistant breast cancer
TL;DR: The role of microRNAs in breast cancer and Estrogen Receptor alpha signaling is broadly summarized and key miRNAs involved in tamoxifen, fulvestrant, and aromatase inhibitor resistance are discussed.
Patent
Materials and methods useful for affecting tumor cell growth, migration and invasion
TL;DR: In this paper, it is disclosed that miR-221 and miR -222 down-regulate PTEN and TIMP3 tumor suppressors, resulting in TRAIL resistance.
Journal ArticleDOI
Effect of zinc supplementation on N-nitrosomethylbenzylamine-induced forestomach tumor development and progression in tumor suppressor-deficient mouse strains
Jin Sun,James Liu,Xueliang Pan,Donald Quimby,Nicola Zanesi,Teresa Druck,Gerd P. Pfeifer,Carlo M. Croce,Louise Y.Y. Fong,Kay Huebner +9 more
TL;DR: Zn supplementation significantly reduced tumor burdens in mice with multiple tumor suppressor deficiencies, and Histological analysis of forestomach tissues showed significant decreases in severity of preneoplastic and neoplastic lesions in Zn-supplemented cohorts of each mouse strain.
Journal Article
Detection of minimal residual disease in leukemic patients with the t(10;14)(q24;q11) chromosomal translocation.
TL;DR: Application of the polymerase chain reaction technology in amplification of the t(10;14)(q24;q11) chromosomal juncture during clinical remission permitted us to increase the detection level of neoplastic cells up to 1 leukemic cell/125,000 normal cells using 1 microgram of DNA.
Journal ArticleDOI
MDM2 Derived from Dedifferentiated Liposarcoma Extracellular Vesicles Induces MMP2 Production from Preadipocytes
Lucia Casadei,Lucia Casadei,Federica Calore,Danielle Braggio,Danielle Braggio,Abeba Zewdu,Abeba Zewdu,Ameya Deshmukh,Paolo Fadda,Gonzalo Lopez,Gonzalo Lopez,Martin Wabitsch,Chi Song,Jennifer L. Leight,Valerie P. Grignol,Valerie P. Grignol,Dina Lev,Carlo M. Croce,Raphael E. Pollock +18 more
TL;DR: Findings indicate thatMDM2 plays a crucial role in DDLPS by enabling crosstalk between tumor cells and the surrounding microenvironment and that targeting vesicular MDM2 could represent a therapeutic option for treating DDL PS.