C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal Article
WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer.
Sai Yendamuri,Tamotsu Kuroki,Francesco Trapasso,Adam C. Henry,Kristoffel R. Dumon,Kay Huebner,Noel N. Williams,Larry R. Kaiser,Carlo M. Croce +8 more
TL;DR: It is concluded that WWOX alterations occur in a significant fraction of lung cancers and may contribute to the pathogenesis of non-small cell lung cancer.
Journal Article
GOK: a gene at 11p15 involved in rhabdomyosarcoma and rhabdoid tumor development.
TL;DR: The hypothesis that loss of GOK expression plays a role in tumor establishment or progression is supported and GOK may act as a recessive tumor suppressor gene in rhabdomyosarcomas and rhabdoid tumors is suggested.
Journal Article
Suppression of Tumorigenicity of Breast Cancer Cells by Microcell-mediated Chromosome Transfer: Studies on Chromosomes 6 and 11
Massimo Negrini,Silvia Sabbioni,Laura Possati,Shashi Rattan,Alfredo Corallini,Giuseppe Barbanti-Brodano,Carlo M. Croce +6 more
TL;DR: The results suggest that each chromosomal arm may contain genes important for the suppression of MCF-7 tumorigenic properties, which are associated with deletions at multiple chromosomal regions.
Journal ArticleDOI
Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model
Elisa Callegari,Bahaeldin K. Elamin,Bahaeldin K. Elamin,Ferdinando Giannone,Maddalena Milazzo,Giuseppe Altavilla,Francesca Fornari,Luciano Giacomelli,Lucilla D'Abundo,Manuela Ferracin,Cristian Bassi,Barbara Zagatti,Fabio Corrà,Elena Miotto,Laura Lupini,Luigi Bolondi,Laura Gramantieri,Carlo M. Croce,Carlo M. Croce,Silvia Sabbioni,Massimo Negrini +20 more
TL;DR: This study establishes that miR‐221 can promote liver tumorigenicity, and establishes a valuable animal model to perform preclinical investigations for the use of anti‐miRNA approaches aimed at liver cancer therapy.
Journal Article
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
Tamotsu Kuroki,Francesco Trapasso,Sai Yendamuri,Ayumi Matsuyama,Hansjuerg Alder,Masaki Mori,Carlo M. Croce +6 more
TL;DR: The findings suggest that hypermethylation of the RAR-beta and FHIT may play an important role in the early stage of esophageal squamous cell carcinogenesis and may be inactivated in accordance with the two-hit inactivation model.