C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Identification of the TCL1 gene involved in T-cell malignancies.
Laura Virgilio,Maria Grazia Narducci,Masaharu Isobe,L G Billips,Max D. Cooper,Carlo M. Croce,Giandomenico Russo +6 more
TL;DR: The TCL1 gene sequence, which, to the authors' knowledge, shows no sequence homology with other human genes, is preferentially expressed early in T- and B-lymphocyte differentiation.
Journal ArticleDOI
Association of a microRNA/TP53 Feedback Circuitry With Pathogenesis and Outcome of B-cell Chronic Lymphocytic Leukemia
Muller Fabbri,Arianna Bottoni,Masayoshi Shimizu,Riccardo Spizzo,Milena S. Nicoloso,Simona Rossi,Elisa Barbarotto,Elisa Barbarotto,Amelia Cimmino,Brett Adair,Sylwia E. Wojcik,Nicola Valeri,Federica Calore,Deepa Sampath,Francesca Fanini,Ivan Vannini,Gerardo Musuraca,Marie Dell'Aquila,Hansjuerg Alder,Ramana V. Davuluri,Laura Z. Rassenti,Massimo Negrini,Tatsuya Nakamura,Dino Amadori,Neil E. Kay,Kanti R. Rai,Michael J. Keating,Thomas J. Kipps,George A. Calin,Carlo M. Croce +29 more
TL;DR: This mechanism provides a novel pathogenetic model for the association of 13q deletions with the indolent form of CLL that involves microRNAs, TP53, and ZAP70 and its downstream effectors.
Journal ArticleDOI
MicroRNA expression profiling using microarrays
TL;DR: The full protocol details of the miRNA microarray assay developed by the group are described here, including miRNA oligo probe design, array fabrication and miRNA target preparation, target-probe hybridization on array, signal detection and data analysis.
Journal ArticleDOI
microRNAs: Master Regulators as Potential Therapeutics in Cancer
Michela Garofalo,Carlo M. Croce +1 more
TL;DR: In insights about how micro- RNAs act as oncogenes and tumor suppressor genes are provided and how these findings can be applied to optimize recent miRNA-based technologies and make them suitable for clinical applications are provided.
Journal ArticleDOI
The miR-17/92 polycistron is up-regulated in Sonic hedgehog-driven medulloblastomas and induced by N-myc in Sonic hedgehog-treated cerebellar neural precursors
Paul A. Northcott,Africa Fernandez-L,John P. Hagan,David W. Ellison,Wesia Grajkowska,Yancey Gillespie,Richard Grundy,Timothy E. Van Meter,James T. Rutka,Carlo M. Croce,Anna Marie Kenney,Michael D. Taylor +11 more
TL;DR: It is concluded that miR-17/92 is a positive effector of Shh-mediated proliferation and that aberrant expression/amplification of this miR confers a growth advantage to medulloblastomas.