C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)
Alexey Palamarchuk,Pearlly S. Yan,Nicola Zanesi,Linan Wang,Benjamin Rodrigues,Mark W. Murphy,Veronica Balatti,Arianna Bottoni,Natalya Nazaryan,Hansjuerg Alder,Laura Z. Rassenti,Thomas J. Kipps,Michael A. Freitas,Carlo M. Croce,Yuri Pekarsky +14 more
TL;DR: Results suggest that inhibition of de novo DNA methylation may be a common oncogenic mechanism in leukemogenesis.
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Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.
Crystina L. Kriss,Javier Pinilla-Ibarz,Adam W. Mailloux,John Powers,Chih-Hang Anthony Tang,Chang Won Kang,Nicola Zanesi,Pearlie K. Epling-Burnette,Eduardo M. Sotomayor,Carlo M. Croce,Juan R. Del Valle,Chih-Chi Andrew Hu +11 more
TL;DR: It is shown for the first time that the previously unexplored endoplasmic reticulum (ER) stress response is aberrantly activated in Eμ-TCL1 mouse and human CLL, and the ER stress-response pathway is a novel molecular target for the treatment of CLL.
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Human urokinase gene is located on the long arm of chromosome 10
Pasquale Tripputi,Francesco Blasi,Pasquale Verde,Linda A. Cannizzaro,Beverly S. Emanuel,Carlo M. Croce +5 more
TL;DR: In this paper, the authors localized the human urokinase gene on the distal third of the long arm (q24-qter) of chromosome 10 by combining somatic cell genetics, in situ hybridization, and Southern hybridization.
Journal ArticleDOI
MicroRNA in Cancer and Cachexia--A Mini-Review.
Mario Acunzo,Carlo M. Croce +1 more
TL;DR: The role of miRNAs in cancer development and cachexia is described and the mechanism through which tumors promote the characteristic distal loss of muscle and fat mass during the cachectic process is still not deeply investigated.
Journal ArticleDOI
Strong inverse correlation between microRNA-125b and human papillomavirus DNA in productive infection.
Gerard J. Nuovo,Xin Wu,Stefano Volinia,Fengting Yan,Gianpiero Di Leva,Nena Chin,Alcina F. Nicol,Jinmai Jiang,Gregory A. Otterson,Thomas D. Schmittgen,Carlo M. Croce +10 more
TL;DR: Infection by the human papillomavirus (HPV) is a cause of cervical intraepithelial neoplasia (CIN) and cancer, and the exogenous application of mimetic miR-125b markedly inhibits HPV DNA synthesis.