C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
Papers
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Journal Article
Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus.
Masaki Mori,Koshi Mimori,Takeshi Shiraishi,Hansjuerg Alder,Hiroshi Inoue,Yoichi Tanaka,Keizo Sugimachi,Kay Huebner,Carlo M. Croce +8 more
TL;DR: The findings indicated that loss of Fhit expression may be an early event in the development of human esophageal carcinoma and may occur even in normal-appearing squamous epithelium in some patients heavily exposed to environmental carcinogens.
Patent
Microrna-based methods and compositions for the diagnosis and treatment of solid cancers
TL;DR: In this article, the levels of at least one miR gene product selected from the group consisting of miR-125b-2, miR 125b-1 and miR 10b were measured for the diagnosis of breast cancer.
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Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
Monica Fedele,Francesca Pentimalli,Gustavo Baldassarre,Sabrina Battista,Andres J. Klein-Szanto,Lawrence C. Kenyon,Rosa Visone,Ivana De Martino,Andrea Ciarmiello,Claudio Arra,Giuseppe Viglietto,Carlo M. Croce,Alfredo Fusco +12 more
TL;DR: Data indicate an oncogenic role of the HMGA1 gene also in vivo and at odds with mice overexpressing a wild-type or a truncated HMGA2 protein, adrenal medullar hyperplasia and pancreatic islet cellhyperplasia frequently occurred and no increase in body size and weight was observed in HM GA1 mice.
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MicroRNAs as therapeutic targets in chemoresistance
Michela Garofalo,Carlo M. Croce +1 more
TL;DR: The involvement of microRNAs in chemotherapy resistance is discussed, recent advancements in the development and delivery of miRNA-based cancer therapeutics are focused on and an attractive anti-tumor approach for integrated cancer therapy is provided.
Journal ArticleDOI
Role of MYC-Regulated Long Noncoding RNAs in Cell Cycle Regulation and Tumorigenesis
Taewan Kim,Young-Jun Jeon,Ri Cui,Ji Hoon Lee,Yong Peng,Sung Hak Kim,Sung Hak Kim,Esmerina Tili,Hansjuerg Alder,Carlo M. Croce +9 more
TL;DR: The role of long noncoding RNAs (lncRNAs) in colorectal cancer (CRC) is less well understood as discussed by the authors, but it is known that the transcription factor MYC is known to regulate lncRNA and has been implicated in cancer cell proliferation and tumorigenesis.