C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers
Masataka Ohta,Hiroshi Inoue,Maria Grazia Cotticelli,Kumar Kastury,Raffaele Baffa,Juan P. Palazzo,Zurab Siprashvili,Masaki Mori,Peter McCue,Teresa Druck,Carlo M. Croce,Kay Huebner +11 more
TL;DR: A 200-300 kb region of chromosome 3p14.2, including the fragile site locus FRA3B, is homozygously deleted in multiple tumor-derived cell lines, allowing identification of the human FHIT gene, a member of ther histidine triad gene family, which encodes a protein with 69% similarity to an S. pombe enzyme.
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An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues
Chang Gong Liu,George A. Calin,Brian Meloon,Nir Gamliel,Cinzia Sevignani,Manuela Ferracin,Calin Dan Dumitru,Masayoshi Shimizu,Simona Zupo,Mariella Dono,Hansjuerg Alder,Florencia Bullrich,Massimo Negrini,Massimo Negrini,Carlo M. Croce +14 more
TL;DR: A recently developed methodology for miRNA gene expression profiling based on the development of a microchip containing oligonucleotides corresponding to 245 miRNAs from human and mouse genomes is described.
Journal ArticleDOI
Oncogenes and cancer.
TL;DR: This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells.
Journal ArticleDOI
The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
Yoshihide Tsujimoto,James Gorham,Jeffrey Cossman,Elaine S. Jaffe,Carlo M. Croce,Carlo M. Croce +5 more
TL;DR: It is concluded that the t(14;18) chromosome translocation is the result of a mistake during the process of VDJ joining at the pre-B-cell stage of differentiation.
Journal ArticleDOI
MicroRNAs in Cancer: Small Molecules With a Huge Impact
Marilena V. Iorio,Carlo M. Croce +1 more
TL;DR: Current knowledge about the involvement of microRNAs in cancer and their potential as diagnostic, prognostic, and therapeutic tools is reviewed.