C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Journal ArticleDOI
The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells.
Damien Saulep-Easton,Fabien B. Vincent,Pin Shie Quah,Andrew H. Wei,Stephen B. Ting,Stephen B. Ting,Carlo M. Croce,Constantine S. Tam,Fabienne Mackay +8 more
TL;DR: It is reported that BAFF signaling promotes IL-10 production by CLL B cells in a mouse model of CLL and in CLL patients, uncovering a major targetable pathway important for the generation of regulatory B cells that is detrimental to immunity in C LL.
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Upregulation of long noncoding RNA MIAT in aggressive form of chronic lymphocytic leukemias
Arash Sattari,Hasan Siddiqui,Farzaneh Moshiri,Apollinaire Ngankeu,Tatsuya Nakamura,Thomas J. Kipps,Carlo M. Croce +6 more
TL;DR: The expression level of MIAT was determined in established leukemia/lymphoma cell lines and found its upregulation in lymphoid but not in myeloid cell lineage with mature B cell phenotype, and it was shown that MIAT constitutes a regulatory loop with OCT4 in malignant mature B Cell, and that both molecules are essential for cell survival.
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Animal models for chronic lymphocytic leukemia.
TL;DR: What has been learned from mice with B‐CLL phenotype is presented and how these mouse models of B-CLL were used to test therapeutic treatments for this common leukemia are presented.
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The human c-ros gene (ROS) is located at chromosome region 6q16----6q22.
Lalitha Nagarajan,Elaine Louie,Yoshihide Tsujimoto,Piero C. Balduzzi,Kay Huebner,Carlo M. Croce +5 more
TL;DR: The c-ros gene joins the c-myb oncogene, which is distal to the c -ros gene on the long arm of human chromosome 6, as a candidate for involvement in chromosome 6q deletions and rearrangements seen in various malignancies.
Journal Article
Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.
TL;DR: DNAs from rodent-human somatic cell hybrids retaining defined complements of human chromosomes were analyzed for the presence of each of the Kox genes, indicating possible zinc finger gene clusters near recurrent chromosomal translocation breakpoints.