C
Carlo M. Croce
Researcher at Ohio State University
Publications - 1156
Citations - 199822
Carlo M. Croce is an academic researcher from Ohio State University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 198, co-authored 1135 publications receiving 189007 citations. Previous affiliations of Carlo M. Croce include University of Nebraska Medical Center & University of California, Los Angeles.
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Patent
Breast cancer biomarker signatures for invasiveness and prognosis
Carlo M. Croce,Stefano Volinia +1 more
TL;DR: In this article, microRNA profiles transition from normal breast to ductal carcinoma in situ and transition to invasive ductal cancer and methods of use thereof are described, including diagnosis and prognosis using microRNA signatures to differentiate invasive from in situ carcinoma.
Journal ArticleDOI
Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical features.
Mark Bloomston,Jeffrey Kneile,Matthew Butterfield,Mary Dillhoff,Peter Muscarella,E. Christopher Ellison,W. Scott Melvin,Carlo M. Croce,Flavia Pichiorri,Kay Huebner,Wendy L. Frankel +10 more
TL;DR: Loss of Fhit and Wwox expression does not predict tumor progression or patient survival, suggesting that loss of expression of genes at the exquisitely replication stress sensitive chromosome fragile regions is an early event in the pathogenesis of cancers of the gallbladder, pancreas, and ampullary cancers.
Book ChapterDOI
Functional assays for specific targeting and delivery of RNA nanoparticles to brain tumor.
Tae Jin Lee,Farzin Haque,Mario Vieweger,Ji Young Yoo,Balveen Kaur,Peixuan Guo,Carlo M. Croce +6 more
TL;DR: Various functional imaging methods are described to evaluate and monitor RNA nanoparticle targeting to intracranial brain tumors in mice to allow in-depth evaluation of specifically delivered RNA therapeutics to brain tumors.
Journal ArticleDOI
"ApoptomiRs" in vascular cells: their role in physiological and pathological angiogenesis.
TL;DR: The current review focuses on the research progress regarding the roles of miRNAs in vascular pathology and their potential therapeutic applications for vascular diseases associated with abnormal angiogenesis, such as cancer.
Journal ArticleDOI
Molecular and Cytogenetical Alterations Induced by Environmental Cigarette Smoke in Mice Heterozygous for Fhit
Silvio De Flora,Francesco D'Agostini,Alberto Izzotti,Nicola Zanesi,Carlo M. Croce,Roumen Balansky +5 more
TL;DR: Although the loss of Fhit protein in the bronchial epithelium of ECS-exposed B6-129(F(1)) mice provides further evidence that the Fhit gene is an early molecular target for ECS, heterozygosity for Fhit does not seem to confer an increased susceptibility of mice in terms of the investigated early biomarkers.