G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Genetic loci influencing kidney function and chronic kidney disease
John C. Chambers,Weihua Zhang,Graham M. Lord,Graham M. Lord,Pim van der Harst,Debbie A Lawlor,Joban Sehmi,Daniel P. Gale,Mark N. Wass,Kourosh R. Ahmadi,Stephan J. L. Bakker,Jacqui Beckmann,Henk J. G. Bilo,Murielle Bochud,Morris J. Brown,Mark J. Caulfield,John M. C. Connell,H. Terence Cook,Ioana Cotlarciuc,George Davey Smith,Ranil de Silva,Guohong Deng,Olivier Devuyst,Lambert D Dikkeschei,Nada Dimkovic,Mark Dockrell,Anna F. Dominiczak,Shah Ebrahim,Thomas Eggermann,Martin Farrall,Luigi Ferrucci,Jürgen Floege,Nita G. Forouhi,Ron T. Gansevoort,Xijin Han,Bo Hedblad,Jaap J. Homan van der Heide,Bouke G. Hepkema,Maria P. Hernandez-Fuentes,Maria P. Hernandez-Fuentes,Elina Hyppönen,Toby Johnson,Paul E. de Jong,Nanne Kleefstra,Vasiliki Lagou,Marta Lapsley,Yun Li,Ruth J. F. Loos,Jian'an Luan,Karin Luttropp,Céline Maréchal,Olle Melander,Patricia B. Munroe,Louise Nordfors,Afshin Parsa,Leena Peltonen,Leena Peltonen,Leena Peltonen,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Brenda W.J.H. Penninx,Esperanza Perucha,Esperanza Perucha,Anneli Pouta,Inga Prokopenko,Paul Roderick,Aimo Ruokonen,Nilesh J. Samani,Serena Sanna,Martin Schalling,David Schlessinger,Georg Schlieper,Marc A. Seelen,Alan R. Shuldiner,Marketa Sjögren,Johannes H. Smit,Johannes H. Smit,Johannes H. Smit,Harold Snieder,Nicole Soranzo,Tim D. Spector,Peter Stenvinkel,Michael J.E. Sternberg,R. Swaminathan,Toshiko Tanaka,L.J. Ubink-Veltmaat,Manuela Uda,Peter Vollenweider,Chris Wallace,Dawn M. Waterworth,Klaus Zerres,Gérard Waeber,Nicholas J. Wareham,Patrick H. Maxwell,Mark I. McCarthy,Marjo-Riitta Järvelin,Vincent Mooser,Gonçalo R. Abecasis,Liz Lightstone,James Scott,Gerjan Navis,Paul Elliott,Jaspal S. Kooner +102 more
TL;DR: Using genome-wide association, common variants at 2p12–p13, 6q26, 17q23 and 19q13 associated with serum creatinine associated with chronic kidney disease are identified.
Journal ArticleDOI
Adult height, nutrition, and population health.
TL;DR: Linkages between adult height and health, within and across generations, suggest that adult height may be a potential tool for monitoring health conditions and that programs focused on offspring outcomes may consider maternal height as a potentially important influence.
Journal ArticleDOI
The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach.
Børge G. Nordestgaard,Tom Palmer,Marianne Benn,Marianne Benn,Jeppe Zacho,Jeppe Zacho,Anne Tybjærg-Hansen,George Davey Smith,Nicholas J. Timpson +8 more
TL;DR: A Mendelian randomization analysis conducted by Børge G. Nordestgaard and colleagues using data from observational studies supports a causal relationship between body mass index and risk for ischemic heart disease.
Journal ArticleDOI
Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis
Caroline Dale,Ghazaleh Fatemifar,Tom Palmer,Jon White,David Prieto-Merino,Delilah Zabaneh,Jorgen Engmann,Tina Shah,Andrew Wong,Helen R. Warren,Stela McLachlan,Stella Trompet,Stella Trompet,Max Moldovan,Richard W Morris,Reecha Sofat,Meena Kumari,Elina Hyppönen,Barbara J. Jefferis,Tom R. Gaunt,Yoav Ben-Shlomo,Yoav Ben-Shlomo,Ang Zhou,Aleksandra Gentry-Maharaj,Andy Ryan,Renée de Mutsert,Raymond Noordam,Mark J. Caulfield,J. Wouter Jukema,Bradford B. Worrall,Patricia B. Munroe,Usha Menon,Usha Menon,Chris Power,Diana Kuh,Debbie A Lawlor,Steve E. Humphries,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Naveed Sattar,Naveed Sattar,Mika Kivimäki,Jacqueline F. Price,George Davey Smith,Frank Dudbridge,Aroon D. Hingorani,Michael V. Holmes,Juan P. Casas,Juan P. Casas +48 more
TL;DR: In this article, the authors quantify and contrast causal associations of central adiposity (waist-to-hip ratio adjusted for body mass index [WHRadjBMI]) and general adiposity with cardiometabolic disease.
Journal ArticleDOI
WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk
Hou-Feng Zheng,Jon H Tobias,Emma L. Duncan,Emma L. Duncan,David M. Evans,Joel Eriksson,Lavinia Paternoster,Laura M. Yerges-Armstrong,Terho Lehtimäki,Ulrica Bergström,Mika Kähönen,Paul Leo,Olli T. Raitakari,Marika Laaksonen,Geoffrey C. Nicholson,Jorma Viikari,Martin Ladouceur,Leo-Pekka Lyytikäinen,Carolina Medina-Gomez,Fernando Rivadeneira,Richard L. Prince,Richard L. Prince,Harri Sievänen,William D. Leslie,Dan Mellström,John A. Eisman,Sofia Movérare-Skrtic,David Goltzman,David A. Hanley,Graeme Jones,Beate St Pourcain,Yongjun Xiao,Nicholas J. Timpson,George Davey Smith,Ian R. Reid,Susan M. Ring,Philip N. Sambrook,Magnus Karlsson,Elaine M. Dennison,John P. Kemp,Patrick Danoy,Adrian Sayers,Scott Wilson,Scott Wilson,Scott Wilson,Maria Nethander,Eugene V. McCloskey,Liesbeth Vandenput,Richard Eastell,Jeff Liu,Tim D. Spector,Braxton D. Mitchell,Elizabeth A. Streeten,Elizabeth A. Streeten,Robert Brommage,Ulrika Pettersson-Kymmer,Matthew A. Brown,Claes Ohlsson,J. Brent Richards,J. Brent Richards,J. Brent Richards,Mattias Lorentzon +61 more
TL;DR: In this article, the authors identify genetic variants associated with cortical bone thickness (CBT) and bone mineral density (BMD) by performing two separate genome-wide association study (GWAS) meta-analyses for CBT in 3 cohorts comprising 5,878 European subjects and for BMD in 5 cohorts consisting 5,672 individuals.