G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Infiltration of the abdominal wall with local anaesthetic after total abdominal hysterectomy has no opioid-sparing effect
TL;DR: It is concluded that infiltration of the deep and superficial layers of the wound of a Pfannenstiel incision with local anaesthetic solution did not confer additional analgesia in patients undergoing major gynaecological surgery.
Journal ArticleDOI
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Vasiliki Lagou,Vasiliki Lagou,Reedik Mägi,Hottenga J-J.,Hottenga J-J.,H Grallert,Perry Jrb.,Nabila Bouatia-Naji,Nabila Bouatia-Naji,Letizia Marullo,D Rybin,Rick Jansen,Josine L. Min,Antigone S. Dimas,Anna Ulrich,L Zudina,Jesper R. Gådin,Longda Jiang,Alessia Faggian,Amélie Bonnefond,Amélie Bonnefond,Amélie Bonnefond,João Fadista,Maria G. Stathopoulou,Aaron Isaacs,Aaron Isaacs,Sara M. Willems,Pau Navarro,Tomohiro Tanaka,Anne U. Jackson,May E. Montasser,Jeffery R. O'Connell,L.F. Bielak,Rebecca J. Webster,Richa Saxena,Jeanette M. Stafford,Beate St Pourcain,N J Timpson,Perttu Salo,Shin S-Y.,Najaf Amin,Albert V. Smith,Guo Li,Niek Verweij,Anuj Goel,Ian Ford,Johnson Pcd.,Johnson Pcd.,Toby Johnson,Karen Kapur,Gudmar Thorleifsson,Rona J. Strawbridge,Rona J. Strawbridge,Rona J. Strawbridge,Laura J. Rasmussen-Torvik,Tõnu Esko,Evelin Mihailov,Tove Fall,Ross M. Fraser,Anubha Mahajan,Anubha Mahajan,Stavroula Kanoni,Stavroula Kanoni,Vilmantas Giedraitis,Marcus E. Kleber,Günther Silbernagel,Joanne M. Meyer,Martina Müller-Nurasyid,Andrea Ganna,Andrea Ganna,Sarin A-P.,Sarin A-P.,Loic Yengo,Loic Yengo,Loic Yengo,Dmitry Shungin,Jian'an Luan,Momoko Horikoshi,Ping An,Serena Sanna,Yvonne Boettcher,Nigel W. Rayner,Nigel W. Rayner,Ilja M. Nolte,Tatijana Zemunik,Erik P A Van Iperen,Peter Kovacs,Nicholas D. Hastie,Sarah H. Wild,Stela McLachlan,Susan Campbell,Ozren Polasek,Olga D. Carlson,Josephine M. Egan,Wieland Kiess,Gonneke Willemsen,Johanna Kuusisto,Markku Laakso,Maria Dimitriou,Andrew A. Hicks,R. Rauramaa,Stefania Bandinelli,Barbara Thorand,Yongmei Liu,Iva Miljkovic,Lars Lind,Alex S. F. Doney,Markus Perola,Markus Perola,Markus Perola,Aroon D. Hingorani,Mika Kivimäki,Meena Kumari,Meena Kumari,Amanda J. Bennett,Christopher J. Groves,Christian Herder,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Leena Kinnunen,Ulf de Faire,Bakker Sjl.,M. I. J. Uusitupa,Palmer Cna.,Joop Jukema,Naveed Sattar,Anneli Pouta,Anneli Pouta,Harold Snieder,Eric Boerwinkle,James S. Pankow,Patrik K. E. Magnusson,Ulrika Krus,Chiara Scapoli,de Geus Ejcn.,de Geus Ejcn.,M Blüher,M Blüher,Wolffenbuttel Bhr.,M. A. Province,Gonçalo R. Abecasis,James B. Meigs,James B. Meigs,G K Hovingh,Jaana Lindström,James F. Wilson,James F. Wilson,Alan F. Wright,George Dedoussis,Stefan R Bornstein,Schwarz Peh.,Anke Tönjes,Winkelmann Br,Bernhard O. Boehm,Winfried März,Winfried März,A. Metspalu,Jackie F. Price,Panagiotis Deloukas,Panagiotis Deloukas,Panagiotis Deloukas,A. Körner,A. Körner,Timo A. Lakka,Sirkka Keinänen-Kiukaanniemi,Sirkka Keinänen-Kiukaanniemi,T. Saaristo,Richard N. Bergman,Jaakko Tuomilehto,Nicholas J. Wareham,Claudia Langenberg,Satu Männistö,Paul W. Franks,Paul W. Franks,Caroline Hayward,Veronique Vitart,Jaakko Kaprio,Sophie Visvikis-Siest,B. Balkau,B. Balkau,David Altshuler,David Altshuler,Igor Rudan,Michael Stumvoll,Harry Campbell,C M van Duijn,C Gieger,Thomas Illig,Luigi Ferrucci,Nancy L. Pedersen,Peter P. Pramstaller,Boehnke M,Timothy M. Frayling,Alan R. Shuldiner,Alan R. Shuldiner,Patricia A. Peyser,Kardia Slr.,Lyle J. Palmer,B.W.J.H. Penninx,Pierre Meneton,T.B. Harris,Gerjan Navis,Harst Pvd.,George Davey Smith,Nita G. Forouhi,Loos Rjf.,Loos Rjf.,Veikko Salomaa,Nicole Soranzo,Dorret I. Boomsma,Leif Groop,Leif Groop,Tiinamaija Tuomi,Albert Hofman,Albert Hofman,Patricia B. Munroe,Vilmundur Gudnason,David S. Siscovick,Hugh Watkins,C. Lecoeur,C. Lecoeur,Peter Vollenweider,Anders Franco-Cereceda,Per Eriksson,Jarvelin M-R.,Jarvelin M-R.,Kari Stefansson,Kari Stefansson,Anders Hamsten,Anders Hamsten,George Nicholson,F Karpe,F Karpe,Emmanouil T. Dermitzakis,Cecilia M. Lindgren,Mark I. McCarthy,Philippe Froguel,Philippe Froguel,Philippe Froguel,Marika Kaakinen,Marika Kaakinen,Valeriya Lyssenko,Valeriya Lyssenko,Richard M. Watanabe,Erik Ingelsson,Erik Ingelsson,Erik Ingelsson,Jose C. Florez,Josée Dupuis,Inês Barroso,Inês Barroso,Inês Barroso,Andrew P. Morris,Inga Prokopenko +254 more
TL;DR: In this paper, the authors assess sex-dimorphic (73,089/50,404 women and 67,506/47,806 men) and sex-combined (151,188/105,056 individuals) fasting glucose/fasting insulin genetic effects via genome-wide association study meta-analyses.
Journal ArticleDOI
Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development.
Michael V. Holmes,Tom G. Richardson,Brian A. Ference,Neil M Davies,Neil M Davies,George Davey Smith +5 more
TL;DR: This Review compares and contrast the use of Mendelian randomization to evaluate potential drug targets versus quantitative traits and explains how genetic epidemiological studies can be used to assess the aetiological roles of biomarkers in disease and to prioritize drug targets, including designing their evaluation in clinical trials.
Journal ArticleDOI
Evidence for reconstructed (001) tungsten obtained by field-ion microscopy
TL;DR: In this article, the atomic structure of clean {001}W was reconstructed by field-ion microscopy, with a reconstruction model with periodic displacements of atoms having vertical components.
Journal ArticleDOI
Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence
Beate St Pourcain,David Skuse,William Mandy,Kai Wang,Kai Wang,Hakon Hakonarson,Nicholas J. Timpson,David M. Evans,David M. Evans,John P. Kemp,John P. Kemp,Susan M. Ring,Wendy L. McArdle,Jean Golding,George Davey Smith +14 more
TL;DR: The findings suggest that measurable common genetic effects for social-communication difficulties vary developmentally and that these changes may affect detectable overlaps with the autism spectrum.