G
George Davey Smith
Researcher at University of Bristol
Publications - 2646
Citations - 294406
George Davey Smith is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Mendelian randomization. The author has an hindex of 224, co-authored 2540 publications receiving 248373 citations. Previous affiliations of George Davey Smith include Keele University & Western Infirmary.
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Journal ArticleDOI
Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review
Lee Hooper,Rachel Thompson,Roger A Harrison,Carolyn Summerbell,Andy R Ness,Helen J Moore,Helen V Worthington,Paul N. Durrington,Julian P T Higgins,Nigel Capps,Rudolph A. Riemersma,Shah Ebrahim,George Davey Smith +12 more
TL;DR: Long chain and shorter chain omega 3 fats do not have a clear effect on total mortality, combined cardiovascular events, or cancer.
Journal ArticleDOI
Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors
TL;DR: The necessary steps for conducting Mendelian randomization investigations using published data are detailed, and novel statistical methods for combining data on the associations of multiple genetic variants with the risk factor and outcome into a single causal effect estimate are presented.
Journal ArticleDOI
Measuring socioeconomic position in health research
TL;DR: It is proposed that there is a greater variation in the association between SEP and health than is generally acknowledged when specific health outcomes are investigated and that studying these variations provide a better understanding of the aetiological mechanisms relating specific diseases with specific exposures.
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Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity
Simone Wahl,Alexander W. Drong,Benjamin Lehne,Marie Loh,Marie Loh,Marie Loh,William R. Scott,William R. Scott,Sonja Kunze,Pei-Chien Tsai,Janina S. Ried,Weihua Zhang,Weihua Zhang,Youwen Yang,Sili Tan,Giovanni Fiorito,Lude Franke,Simonetta Guarrera,Silva Kasela,Jennifer Kriebel,Rebecca C Richmond,Marco Adamo,Uzma Afzal,Uzma Afzal,Mika Ala-Korpela,Mika Ala-Korpela,Mika Ala-Korpela,Benedetta Albetti,Ole Ammerpohl,Jane F. Apperley,Marian Beekman,Pier Alberto Bertazzi,S. Lucas Black,Christine Blancher,Marc Jan Bonder,Mario Brosch,Maren Carstensen-Kirberg,Anton J. M. de Craen,Simon de Lusignan,Abbas Dehghan,Mohamed Elkalaawy,Krista Fischer,Oscar H. Franco,Tom R. Gaunt,Jochen Hampe,Majid Hashemi,Aaron Isaacs,Andrew Jenkinson,Sujeet Jha,Norihiro Kato,Vittorio Krogh,Michael Laffan,Christa Meisinger,Thomas Meitinger,Zuan Yu Mok,Valeria Motta,Hong Kiat Ng,Zacharoula Nikolakopoulou,Georgios Nteliopoulos,Salvatore Panico,Natalia Pervjakova,Holger Prokisch,Wolfgang Rathmann,Michael Roden,Federica Rota,Michelle Ann Rozario,Johanna K. Sandling,Johanna K. Sandling,Clemens Schafmayer,Katharina Schramm,Reiner Siebert,Reiner Siebert,P. Eline Slagboom,Pasi Soininen,Pasi Soininen,Lisette Stolk,Konstantin Strauch,E-Shyong Tai,Letizia Tarantini,Barbara Thorand,Ettje F. Tigchelaar,Rosario Tumino,André G. Uitterlinden,Cornelia M. van Duijn,Joyce B. J. van Meurs,Paolo Vineis,Ananda R. Wickremasinghe,Cisca Wijmenga,Tsun-Po Yang,Wei Yuan,Wei Yuan,Alexandra Zhernakova,Rachel L. Batterham,George Davey Smith,Panos Deloukas,Panos Deloukas,Panos Deloukas,Bastiaan T. Heijmans,Christian Herder,Albert Hofman,Cecilia M. Lindgren,Cecilia M. Lindgren,Lili Milani,Pim van der Harst,Annette Peters,Thomas Illig,Caroline L Relton,Melanie Waldenberger,Marjo-Riitta Järvelin,Valentina Bollati,Richie Soong,Tim D. Spector,James Scott,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Paul Elliott,Paul Elliott,Jordana T. Bell,Giuseppe Matullo,Christian Gieger,Jaspal S. Kooner,Harald Grallert,John C. Chambers +123 more
TL;DR: In this article, the authors used epigenome-wide association to show that body mass index (BMI), a key measure of adiposity, is associated with widespread changes in DNA methylation.
Journal ArticleDOI
Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study
Robert Carreras-Torres,Mattias Johansson,Philip C Haycock,Kaitlin H Wade,Caroline L Relton,Richard M. Martin,Richard M. Martin,George Davey Smith,Demetrius Albanes,Melinda C. Aldrich,Angeline S. Andrew,Susanne M. Arnold,Heike Bickeböller,Stig E. Bojesen,Hans Brunnström,Jonas Manjer,Irene Brüske,Neil E. Caporaso,Chu Chen,David C. Christiani,W. Jay Christian,Jennifer A. Doherty,Eric J. Duell,John K. Field,Michael P.A. Davies,Michael W. Marcus,Gary E. Goodman,Kjell Grankvist,Aage Haugen,Yun-Chul Hong,Lambertus A. Kiemeney,Erik H.F.M. van der Heijden,Peter Kraft,Mikael Johansson,Stephen Lam,Maria Teresa Landi,Philip Lazarus,Loic Le Marchand,Geoffrey Liu,Olle Melander,Sungshim L. Park,Gad Rennert,Angela Risch,Eric B. Haura,Ghislaine Scelo,David Zaridze,Anush Mukeriya,Milan Savic,Jolanta Lissowska,Beata Swiatkowska,Vladimir Janout,Ivana Holcatova,Dana Mates,Matthew B. Schabath,Hongbing Shen,Adonina Tardón,M. Dawn Teare,Penella J. Woll,Ming-Sound Tsao,Xifeng Wu,Jian-Min Yuan,Rayjean J. Hung,Christopher I. Amos,James D. McKay,Paul Brennan +64 more
TL;DR: The results are consistent with a causal role of fasting insulin and low-density lipoprotein cholesterol in lung cancer etiology, as well as for BMI in squamous cell and small cell carcinoma, and the latter relation may be mediated by a previously unrecognized effect of obesity on smoking behavior.