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Iris E. C. Sommer

Researcher at University Medical Center Groningen

Publications -  454
Citations -  20580

Iris E. C. Sommer is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Schizophrenia & Medicine. The author has an hindex of 68, co-authored 394 publications receiving 16545 citations. Previous affiliations of Iris E. C. Sommer include University of Toronto & University of Michigan.

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Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: An immunocytological study in the central nervous system

TL;DR: In this article, four monoclonal antibodies are characterized from a fusion of mouse myeloma P3-NS1/1-Ag4-1 with spleen cells from BALB/c mice immunized with white matter from bovine corpus callosum.
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Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1.

TL;DR: It is shown here that a carbohydrate moiety recognized by L2 and HNK-1 monoclonal antibodies, is present in mouse N-CAM and LI, which points to a previously undetected molecular diversity which may have functional implications for modulating cell adhesion during development.
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Should we expand the toolbox of psychiatric treatment methods to include Repetitive Transcranial Magnetic Stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders.

TL;DR: It is time to provide rTMS as a clinical treatment method for depression, for auditory verbal hallucinations, and possibly for negative symptoms, as well as for electroconvulsive treatment for depression.
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The genetic architecture of the human cerebral cortex

Katrina L. Grasby, +359 more
- 20 Mar 2020 - 
TL;DR: Results support the radial unit hypothesis that different developmental mechanisms promote surface area expansion and increases in thickness and find evidence that brain structure is a key phenotype along the causal pathway that leads from genetic variation to differences in general cognitive function.