Institution
California State University, Long Beach
Education•Long Beach, California, United States•
About: California State University, Long Beach is a education organization based out in Long Beach, California, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 10036 authors who have published 13933 publications receiving 377394 citations. The organization is also known as: Cal State Long Beach & Long Beach State.
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TL;DR: Novel and rapid mechanisms by which E2 prevents chemotherapy or radiation-induced apoptosis of breast cancer, probably mediated through the plasma membrane estrogen receptor are reported.
Abstract: Chemotherapy or irradiation treatment induces breast cancer cell apoptosis, but this can be limited by estradiol (E2) through unknown mechanisms. To investigate this, we subjected estrogen receptor-expressing human breast cancer cells (MCF-7 and ZR-75–1) to paclitaxel (taxol) or to UV irradiation. Marked increases in cell apoptosis were induced, but these were significantly reversed by incubation with E2. Taxol or UV stimulated c-Jun N-terminal kinase (JNK) activity, which was inhibited by E2. Expression of a dominant-negative Jnk-1 protein strongly prevented taxol- or UV-induced apoptosis, whereas E2 inhibition of apoptosis was reversed by expression of constituitively active Jnk-1. As targets for participation in apoptosis, Bcl-2 and Bcl-xl were phosphorylated in response to JNK activation by taxol or UV; this was prevented by E2. Taxol or UV activated caspase activity in a JNK-dependent fashion and caused the cleavage of procaspase-9 to caspase-9, each inhibited by E2. Independently, the steroid also a...
234 citations
TL;DR: In this paper, the authors experimentally examined some situational influences on the formation and consequences of two brand image beliefs, pertaining to fun and sophistication (classiness), and established that nonverbalized personality associations of celebrity endorsers on these dimensions can indeed reinforce equivalent consumer beliefs about a brand's fun and classiness benefits.
234 citations
TL;DR: The authors explored two competing hypotheses about social-sexual behavior at work, which they defined as any non-work-related behavior having a sexual component, including harassment, flirting, and m...
Abstract: This study explored two competing hypotheses about social-sexual behavior at work, which we defined as any non-work-related behavior having a sexual component, including harassment, flirting, and m...
233 citations
233 citations
TL;DR: The authors conducted meta-analyses of relationships involving positive and negative ad-evoked feelings to determine whether the effects of positive or negative feelings on advertising responses were significant. But their results were limited.
Abstract: The authors conduct meta-analyses of relationships involving positive and negative ad-evoked feelings to determine (1) whether the effects of positive and negative feelings on advertising responses...
233 citations
Authors
Showing all 10093 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| David A. Weitz | 178 | 1038 | 114182 |
| Menachem Elimelech | 157 | 547 | 95285 |
| Josh Moss | 139 | 1019 | 89255 |
| Ron D. Hays | 135 | 781 | 82285 |
| Matthew J. Budoff | 125 | 1449 | 68115 |
| Harinder Singh Bawa | 120 | 798 | 66120 |
| Kamyar Kalantar-Zadeh | 118 | 1025 | 56187 |
| Dionysios D. Dionysiou | 116 | 675 | 48449 |
| Kathryn Grimm | 110 | 618 | 47814 |
| Richard B. Kaner | 106 | 557 | 66862 |
| William Oh | 100 | 867 | 48760 |
| Nosratola D. Vaziri | 98 | 708 | 34586 |
| Jagat Narula | 98 | 978 | 47745 |
| Qichun Zhang | 94 | 540 | 28367 |
| Muhammad Shahbaz | 92 | 1001 | 34170 |