Georgia College & State University

About: Georgia College & State University is a education organization based out in Milledgeville, Georgia, United States. It is known for research contribution in the topics: Population & Context (language use). The organization has 950 authors who have published 1591 publications receiving 37027 citations.

Recent trends and developments in e-banking in an underdeveloped nation – an empirical study

Abstract: This paper describes a case study about the major issues and challenges in the development of the electronic banking (e-banking) industry of a relatively underdeveloped nation. This research shows that even in many less developed nations, the application of e-banking can help their local banks reduce operating costs and provide a better and fast service to their customers. The research objectives are to investigate the current trends and developments in e-banking and provide managerial insights for the banking industry in those underdeveloped nations. The collected data are examined through statistical analysis tools. Managerial implications are discussed with suggestions for future research.

Standardized Patient Encounters and Individual Case-Based Simulations Improve Students' Confidence and Promote Reflection: A Preliminary Study

Abstract: Context: Simulations and standardized patient (SP) encounters are used to provide clinical experiences for students. In athletic training, no research has examined the perceived educational benefit...

Visuospatial functions in the rat following injuries to striate, peristriate, and parietal neocortical sites

Abstract: The influence of lesions located generally within four regions of the rat#’s posterior neocortex upon the acquisition and retention of two-choice visual discriminations was assessed using a Thompson-Bryant apparatus. The ability to distinguish visual patterns was tested by utilizing stimuli composed of 45° versus 135° alternating black and white stripes (both total and local luminance cues were controlled). “Brightness” discrimination was assessed by using black and white card discriminanda. Posterior parietal injuries resulted in a dysfunction on each of the four tasks, but rats with this injury eventually attained criterion for each of the habits. Smaller, more anteromedial parietal lesions failed to disturb pattern discrimination and were not studied in the other paradigms. The only deficit observed in rats with medial peristriate injuries was a slight retardation in acquisition of the pattern discrimination. Since the effects of lateral peristriate and striate injuries upon pattern vision have been well described previously, the effects of these lesions on the retention and acquisition of the black-white discrimination were studied. Lateral peristriate lesions, but not striate lesions, were associated with a retention loss of the brightness problem. This loss was detected even with a recovery interval of 60 days. Both striate and lateral peristriate lesions retarded black-white discrimination acquisition. Discussion focuses on the probable natures of the visual dysfunctions associated with these injuries.

The proteasome and epigenetics: zooming in on histone modifications.

Abstract: The proteasome is a structural complex of many proteins that degrades substrates marked by covalent linkage to ubiquitin. Many years of research has shown a role for ubiquitin-proteasome-mediated proteolysis in synaptic plasticity and memory mainly in degrading synaptic, cytoplasmic and nuclear proteins. Recent work indicates that the proteasome has wider proteolytic and non-proteolytic roles in processes such as histone modifications that affect synaptic plasticity and memory. In this review, we assess the evidence gathered from neuronal as well as non-neuronal cell types regarding the function of the proteasome in positive or negative regulation of posttranslational modifications of histones, such as acetylation, methylation and ubiquitination. We discuss the critical roles of the proteasome in clearing excess histone proteins in various cellular contexts and the possible non-proteolytic functions in regulating transcription of target genes. In addition, we summarize the current literature on diverse chromatin-remodeling machineries, such as histone acetyltransferases, deacetylates, methyltransferases and demethylases, as targets for proteasomal degradation across experimental models. Lastly, we provide a perspective on how proteasomal regulation of histone modifications may modulate synaptic plasticity in the nervous system.

The Eocene Thomas Ranch flora, Allenby Formation, Princeton, British Columbia, Canada

Abstract: A flora from Thomas Ranch near Princeton, British Columbia, Canada, is assessed for biodiversity and paleoclimate. This latest Early to early Middle Eocene flora occurs in the Allenby Formation. Seventy-six megafossil morphotypes have been recognized, representing at least 62 species, with 29 identified to genus or species. Common taxa include Ginkgo L., Metasequoia Miki, Sequoia Endl., Abies Mill., Pinus L., Pseudolarix Gordon, Acer L., Alnus Mill., Betula L., Fagus L., Sassafras J Presl, Macginitiea Wolfe & Wehr, Prunus L., and Ulmus L. More than 70 pollen and spore types are recognized, 32 of which are assignable to family or genus. The microflora is dominated by conifers (85%–97% abundance), with Betulaceae accounting for most of the angiosperms. The Climate Leaf Analysis Multivariate Program (CLAMP) calculates a mean annual temperature (MAT) of 9.0 ± 1.7 °C and bioclimatic analysis (BA) calculates a MAT of 12.8 ± 2.5 °C. Coldest month mean temperature (CMMT) was >0 °C. Mean annual precipitation (MAP)...