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Institution

Osaka University

EducationOsaka, Japan
About: Osaka University is a education organization based out in Osaka, Japan. It is known for research contribution in the topics: Laser & Catalysis. The organization has 83778 authors who have published 185669 publications receiving 5158122 citations. The organization is also known as: Ōsaka daigaku.
Topics: Laser, Catalysis, Population, Gene, Thin film


Papers
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Journal ArticleDOI
TL;DR: In this paper, a detailed elemental abundance analysis of 32 dwarfs and subgiant stars in the Galactic bulge is presented, based on high-resolution spectra obtained during gravitational microlensing events.
Abstract: Based on high-resolution spectra obtained during gravitational microlensing events we present a detailed elemental abundance analysis of 32 dwarf and subgiant stars in the Galactic bulge. Combined with the sample of 26 stars from the previous papers in this series, we now have 58 microlensed bulge dwarfs and subgiants that have been homogeneously analysed. The main characteristics of the sample and the findings that can be drawn are: (i) the metallicity distribution (MDF) is wide and spans all metallicities between [Fe/H] = −1.9 to +0.6; (ii) the dip in the MDF around solar metallicity that was apparent in our previous analysis of a smaller sample (26 microlensed stars) is no longer evident; instead it has a complex structure and indications of multiple components are starting to emerge. A tentative interpretation is that there could be different stellar populations at interplay, each with a different scale height: the thin disk, the thick disk, and a bar population; (iii) the stars with [Fe/H] ≲ −0.1 are old with ages between 10 and 12 Gyr; (iv) the metal-rich stars with [Fe/H] ≳ −0.1 show a wide variety of ages, ranging from 2 to 12 Gyr with a distribution that has a dominant peak around 4−5 Gyr and a tail towards higher ages; (v) there are indications in the [α/Fe]−[Fe/H] abundance trends that the “knee” occurs around [Fe/H] = −0.3 to −0.2, which is a slightly higher metallicity as compared to the “knee” for the local thick disk. This suggests that the chemical enrichment of the metal-poor bulge has been somewhat faster than what is observed for the local thick disk. The results from the microlensed bulge dwarf stars in combination with other findings in the literature, in particular the evidence that the bulge has cylindrical rotation, indicate that the Milky Way could be an almost pure disk galaxy. The bulge would then just be a conglomerate of the other Galactic stellar populations (thin disk, thick disk, halo, and ...?), residing together in the central parts of the Galaxy, influenced by the Galactic bar.

470 citations

Journal ArticleDOI
TL;DR: In this article, the authors discuss recent progress in the explorations of topological materials beyond topological insulators; specifically, they focus on topological crystalline insulators and bulk topological superconductors.
Abstract: In this review, we discuss recent progress in the explorations of topological materials beyond topological insulators; specifically, we focus on topological crystalline insulators and bulk topological superconductors. The basic concepts, model Hamiltonians, and novel electronic properties of these new topological materials are explained. The key role of symmetries that underlie their topological properties is elucidated. Key issues in their materials realizations are also discussed.

470 citations

Journal ArticleDOI
TL;DR: Analysis of knockout mice revealed a pivotal role for MyD88 in the signaling of the TLR/IL-1R family, and together, TLRs and the downstream signaling pathway play a key role in innate immune recognition and in subsequent activation of adaptive immunity.

470 citations

Journal ArticleDOI
TL;DR: This Primer provides a mechanistic overview of how Sox family proteins function, as a paradigm for transcriptional regulation of development involving multi-transcription factor complexes, and discusses how Sox factors can thus regulate diverse processes during development.
Abstract: Sox transcription factors play widespread roles during development; however, their versatile funtions have a relatively simple basis: the binding of a Sox protein alone to DNA does not elicit transcriptional activation or repression, but requires binding of a partner transcription factor to an adjacent site on the DNA. Thus, the activity of a Sox protein is dependent upon the identity of its partner factor and the context of the DNA sequence to which it binds. In this Primer, we provide an mechanistic overview of how Sox family proteins function, as a paradigm for transcriptional regulation of development involving multi-transcription factor complexes, and we discuss how Sox factors can thus regulate diverse processes during development.

469 citations

Journal ArticleDOI
TL;DR: It is shown that it is possible to disentangle the various mechanisms and unambiguously extract the important neutrino-mass scale, if all the signatures of the reaction are searched for in a sufficient number of nuclear isotopes.
Abstract: Neutrinoless double-beta decay, which is a very old and yet elusive process, is reviewed. Its observation will signal that the lepton number is not conserved and that the neutrinos are Majorana particles. More importantly it is our best hope for determining the absolute neutrino-mass scale at the level of a few tens of meV. To achieve the last goal certain hurdles must be overcome involving particle, nuclear and experimental physics. Nuclear physics is important for extracting useful information from the data. One must accurately evaluate the relevant nuclear matrix elements--a formidable task. To this end, we review the sophisticated nuclear structure approaches which have recently been developed, and which give confidence that the required nuclear matrix elements can be reliably calculated employing different methods: (a) the various versions of the quasiparticle random phase approximations, (b) the interacting boson model, (c) the energy density functional method and (d) the large basis interacting shell model. It is encouraging that, for the light neutrino-mass term at least, these vastly different approaches now give comparable results. From an experimental point of view it is challenging, since the life times are long and one has to fight against formidable backgrounds. One needs large isotopically enriched sources and detectors with high-energy resolution, low thresholds and very low background. If a signal is found, it will be a tremendous accomplishment. The real task then, of course, will be the extraction of the neutrino mass from the observations. This is not trivial, since current particle models predict the presence of many mechanisms other than the neutrino mass, which may contribute to or even dominate this process. In particular, we will consider the following processes: The neutrino induced, but neutrino-mass independent contribution. Heavy left and/or right-handed neutrino-mass contributions. Intermediate scalars (doubly charged, etc). Supersymmetric (SUSY) contributions. We will show that it is possible to disentangle the various mechanisms and unambiguously extract the important neutrino-mass scale, if all the signatures of the reaction are searched for in a sufficient number of nuclear isotopes.

469 citations


Authors

Showing all 84130 results

NameH-indexPapersCitations
Shizuo Akira2611308320561
Thomas C. Südhof191653118007
Tadamitsu Kishimoto1811067130860
Yusuke Nakamura1792076160313
H. S. Chen1792401178529
Hyun-Chul Kim1764076183227
Masayuki Yamamoto1711576123028
Kenji Kangawa1531117110059
Jongmin Lee1502257134772
Yoshio Bando147123480883
Takeo Kanade147799103237
Olaf Reimer14471674359
Yuji Matsuzawa143836116711
Kim Nasmyth14229459231
Tasuku Honjo14171288428
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023139
2022637
20216,915
20206,865
20196,462
20186,189