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Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary

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In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Abstract
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.

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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI

Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis.

TL;DR: Aortic stiffness expressed as aortic PWV is a strong predictor of future CV events and all-cause mortality and the predictive ability of arterial stiffness is higher in subjects with a higher baseline CV risk.
References
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Journal ArticleDOI

Noninvasive Pulse Wave Analysis for the Early Detection of Vascular Disease

TL;DR: Application of the technique to subjects with hypertension, postmenopausal women with symptomatic coronary artery disease, and appropriate control subjects has confirmed a reduction of oscillatory compliance in the disease states and an increase in capacitive and oscillatory compliances in response to vasodilator drugs.
Journal ArticleDOI

Regional wave travel and reflections along the human aorta: a study with six simultaneous micromanometric pressures.

TL;DR: The geometric and elastic nonuniformity of the aorta results in two major sites of arterial wave reflection that influence the aORTic pressure waveforms in man.
Journal ArticleDOI

Diabetes Mellitus, Aortic Stiffness, and Cardiovascular Mortality in End-Stage Renal Disease

TL;DR: It is demonstrated that the increased aortic stiffness of the ESRD patients with diabetes mellitus contributed to the higher all-cause and cardiovascular mortality rates.
Journal ArticleDOI

Improvement in Blood Pressure, Arterial Stiffness and Wave Reflections With a Very-Low-Dose Perindopril/Indapamide Combination in Hypertensive Patient: A Comparison With Atenolol

TL;DR: The very-low-dose combination Per/Ind normalizes SBP, PP, and arterial function to a significantly larger extent than does atenolol, a hemodynamic profile that is known to improve survival in hypertensive populations with high cardiovascular risk.
Journal ArticleDOI

Assessment of arterial stiffness in clinical practice

TL;DR: It will become necessary for physicians both in primary care and hospital practice to understand the importance of arterial stiffness and the techniques available for its clinical assessment, which will be the focus of this review.
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