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Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary

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TLDR
In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Abstract
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.

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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI

Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis.

TL;DR: Aortic stiffness expressed as aortic PWV is a strong predictor of future CV events and all-cause mortality and the predictive ability of arterial stiffness is higher in subjects with a higher baseline CV risk.
References
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Journal ArticleDOI

Noninvasive determination of aortic input impedance and external left ventricular power output: a validation and repeatability study of a new technique.

TL;DR: Measurement of noninvasive impedance by this technique provides an accurate and repeatable assessment of mean and pulsatile cardiac load.
Journal ArticleDOI

Heart rate dependency of pulse pressure amplification and arterial stiffness

TL;DR: Data suggest that peripheral pulse pressure does not provide an accurate assessment of changes in central hemodynamics in relation to changes in heart rate, and that aortic stiffness is not affected by acute changes inHeart rate.
Journal ArticleDOI

Heart Rate An Important Confounder of Pulse Wave Velocity Assessment

TL;DR: This study demonstrates that HR is an important factor in the intraindividual variation of PWV in elderly subjects, and raises methodological concern about the measurement of this parameter.
Journal ArticleDOI

Methods and devices for measuring arterial compliance in humans

TL;DR: This article summarizes the discussion of the dedicated Task Force during the first Conference of Consensus on Arterial Stiffness held in June 2000 (Paris, France) and analyses methods and devices used worldwide to evaluate the arterial stiffness.
Journal ArticleDOI

Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions

TL;DR: Increased arterial wave reflections are independently associated with an increased risk for severe short- and long-term cardiovascular events in patients undergoing PCI.
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