Open AccessJournal Article
Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary
Michael F. O'Rourke,Stanley S. Franklin,Stéphane Laurent,John R. Cockcroft,Luc M. Van Bortel,Pierre Boutouyrie,Cristina Giannattasio,Daniel Hayoz,Bruno Pannier,Charalambos Vlachopoulos,Ian B. Wilkinson,Harry A.J. Struijker-Boudier +11 more
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In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.Abstract:
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.read more
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Circulating endothelial progenitor cells and large artery structure and function in young subjects with uncomplicated Type 1 Diabetes
Carlo Palombo,Michaela Kozakova,Carmela Morizzo,L. Gnesi,Maria Chiara Barsotti,Paolo Spontoni,Francesco Massart,Paolo Salvi,Alberto Balbarini,Giuseppe Saggese,Rossella Di Stefano,Giovanni Federico +11 more
TL;DR: It is suggested that young subjects with relatively long-lasting T1DM have a generalized preclinical involvement of large artery structure and function, as well as a blunted endothelium regenerating capacity.
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Effects of resistance training on central blood pressure in obese young men
Daniel M. Croymans,Shannon L. Krell,C S Oh,Michael Katiraie,C Y Lam,Ryan A. Harris,Christian K. Roberts +6 more
TL;DR: In overweight/obese young men, high-intensity RT decreases cSBP, independently of weight loss and changes in arterial stiffness, and the cardioprotective effects of RT may be related to effects on central blood pressure.
Journal ArticleDOI
Assessment of ascending aorta wall stiffness in hypertensive patients by tissue Doppler imaging and strain Doppler echocardiography
Antonio Vitarelli,Marcello Giordano,Giuseppe Germanò,Mario Pergolini,Paolo Cicconetti,Francesco Tomei,Angela Sancini,Daniela Battaglia,Olga Dettori,Lidia Capotosto,Valentina De Cicco,Melissa De Maio,Massimo Vitarelli,Pasqualina Bruno +13 more
TL;DR: Ascending aorta TDI provides wall velocity and strain data differentiating hypertensive from healthy adults and reflecting aortic compliance changes related to age and sex and LV diastolic function.
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Cardio-ankle vascular index predicts for the incidence of cardiovascular events in obese patients: A multicenter prospective cohort study (Japan Obesity and Metabolic Syndrome Study: JOMS)
Noriko Satoh-Asahara,Kazuhiko Kotani,Hajime Yamakage,Tsutomu Yamada,Rika Araki,Taiichiro Okajima,Masahiro Adachi,Mariko Oishi,Akira Shimatsu +8 more
TL;DR: It is demonstrated for the first time that CAVI is an effective predictor of CVD events in obese patients and added value to atherosclerotic cardiovascular disease risk score in predicting the development of CVC.
Journal ArticleDOI
The Noninvasive Assessment of Vascular Aging
TL;DR: The major principles of the measurement of arterial stiffness are described and the amount of epidemiologic evidence obtained with a given method regarding the predictive value of arterials stiffness for CV events is analyzed.
References
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The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report.
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: The most effective therapy prescribed by the most careful clinician will control hypertension only if patients are motivated, and empathy builds trust and is a potent motivator.
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Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: In those older than age 50, systolic blood pressure of greater than 140 mm Hg is a more important cardiovascular disease (CVD) risk factor than diastolic BP, and hypertension will be controlled only if patients are motivated to stay on their treatment plan.
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Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
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Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.
Stéphane Laurent,Pierre Boutouyrie,Roland Asmar,Isabelle Gautier,Brigitte Laloux,Louis Guize,Pierre Ducimetière,Athanase Benetos +7 more
TL;DR: This study provides the first direct evidence that aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with essential hypertension.
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Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial
Björn Dahlöf,Peter S. Sever,Neil R Poulter,Hans Wedel,D Gareth Beevers,Mark J. Caulfield,Rory Collins,Sverre E. Kjeldsen,Arni Kristinsson,Gordon T. McInnes,Jesper Mehlsen,Markku S. Nieminen,Eoin O'Brien,Jan Östergren +13 more
TL;DR: The amlodipine-based regimen prevented more major cardiovascular events and induced less diabetes than the atenolol- based regimen, and these effects might not be entirely explained by better control of blood pressure.
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