Open AccessJournal Article
Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary
Michael F. O'Rourke,Stanley S. Franklin,Stéphane Laurent,John R. Cockcroft,Luc M. Van Bortel,Pierre Boutouyrie,Cristina Giannattasio,Daniel Hayoz,Bruno Pannier,Charalambos Vlachopoulos,Ian B. Wilkinson,Harry A.J. Struijker-Boudier +11 more
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In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.Abstract:
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.read more
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Systemic Vascular Dysfunction in Patients With Chronic Mountain Sickness
Stefano F. Rimoldi,Stefano F. Rimoldi,Emrush Rexhaj,Emrush Rexhaj,Lorenza Pratali,Damian M. Bailey,Damian Hutter,Francesco Faita,Carlos Salinas Salmòn,Mercedes Villena,Pascal Nicod,Yves Allemann,Urs Scherrer,Urs Scherrer,Claudio Sartori +14 more
TL;DR: Patients with CMS show marked systemic vascular dysfunction that may predispose them to increased systemic cardiovascular morbidity and structural and functional alterations contribute to this problem that might predispose these patients to premature cardiovascular disease.
Journal ArticleDOI
Ambulatory arterial stiffness index, pulse wave velocity and augmentation index--interchangeable or mutually exclusive measures?
TL;DR: The present study examines three different measures of arterial stiffness – pulse wave velocity, wave reflection and AASI in a large hypertensive population, comparing their determinants and intercorrelations, both unadjusted and adjusted for confounders, and proposes that the measures should not be considered interchangeable.
Journal ArticleDOI
Arterial Stiffness and Hypertension in the Elderly.
TL;DR: This review will address the issues of the cellular and molecular mechanisms of arterial stiffening in elderly hypertensives, the consequences of arterials stiffening on central systolic and pulse pressures and target organs, the methodology for measuring arterial stiffness, central pulse pressure and wave reflection, and how the concepts of EVA and SUPERNOVA apply to the detection of organ damage and prevention of CV complications.
Journal ArticleDOI
Noninvasive estimation of aortic stiffness through different approaches: comparison with intra-aortic recordings
Paolo Salvi,Filippo Scalise,Matteo Rovina,Francesco Moretti,Lucia Salvi,Andrea Grillo,Lan Gao,Corrado Baldi,Andrea Faini,Giulia Furlanis,A. Sorropago,Sandrine Millasseau,Giovanni Sorropago,Renzo Carretta,Alberto Avolio,Gianfranco Parati +15 more
TL;DR: Only those assessing carotid-femoral pulse wave velocity (Complior Analyse, Pulse pen ETT, PulsePen ET, and SphygmoCor) appear to be reliable approaches for estimation of aortic stiffness.
Journal ArticleDOI
Can assisted reproductive technologies cause adult-onset disease? Evidence from human and mouse.
TL;DR: The current epidemiological evidence that ART-conceived children have detectable differences in blood pressure, body composition, and glucose homeostasis is presented and it is proposed that the mouse system can be used to adequately study, modify, and improve outcomes for ART children.
References
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Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
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2007 Guidelines for the Management of Arterial Hypertension : The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).
Giuseppe Mancia,Guy De Backer,Anna F. Dominiczak,Renata Cifkova,Robert Fagard,Giuseppe Germanò,Guido Grassi,Anthony M. Heagerty,Sverre E. Kjeldsen,Stéphane Laurent,Krzysztof Narkiewicz,Luis M. Ruilope,Andrzej Rynkiewicz,Roland E. Schmieder,Harry A.J. Struijker Boudier,Alberto Zanchetti +15 more
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Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.
Stéphane Laurent,Pierre Boutouyrie,Roland Asmar,Isabelle Gautier,Brigitte Laloux,Louis Guize,Pierre Ducimetière,Athanase Benetos +7 more
TL;DR: This study provides the first direct evidence that aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with essential hypertension.
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Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial
Björn Dahlöf,Peter S. Sever,Neil R Poulter,Hans Wedel,D Gareth Beevers,Mark J. Caulfield,Rory Collins,Sverre E. Kjeldsen,Arni Kristinsson,Gordon T. McInnes,Jesper Mehlsen,Markku S. Nieminen,Eoin O'Brien,Jan Östergren +13 more
TL;DR: The amlodipine-based regimen prevented more major cardiovascular events and induced less diabetes than the atenolol- based regimen, and these effects might not be entirely explained by better control of blood pressure.
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