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Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary

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TLDR
In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Abstract
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.

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Surrounding tissues affect the passive mechanics of the vessel wall: theory and experiment.

TL;DR: Experimental data support the proposed hypothesis that the surrounding tissue takes up a considerable portion of the intravascular pressure and significantly reduces the wall strain and stress and suggest that in vitro and in vivo measurements of the mechanical properties of vessels must be interpreted with consideration of the constraint of the surrounds tissue.
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Long-term reduction in aortic stiffness: a 5.3-year follow-up in routine clinical practice.

TL;DR: It is indicated that a large and sustained decrease in aortic stiffness can be obtained in treated hypertensive patients under conditions of routine clinical practice, and likely represents a delayed response to the long-term normalization of BP and cardiovascular risk factors, through arterial remodeling.
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Determinants of Aortic Stiffness: 16-Year Follow-Up of the Whitehall II Study

TL;DR: In this large prospective study, central obesity was a strong predictor of aortic stiffness and heart rate in men and adiponectin in women predicted aortIC pulse wave velocity suggesting that strategies to prevent aorti stiffening should be focused differently by sex.
Journal ArticleDOI

Depression, Anxiety, and Arterial Stiffness

TL;DR: Current depressive or anxiety disorders were associated with a higher central augmentation index, a manifestation of early wave reflection because of arterial stiffness, which may enhance the development and progression of atherosclerosis and other cardiovascular conditions.
Journal ArticleDOI

Validating a new oscillometric device for aortic pulse wave velocity measurements in children and adolescents.

TL;DR: Vicorder aPWV values are similar to those obtained by SphygmoCor applanation tonometry and make Vicorder appropriate for large multicentre studies in children and adolescents.
References
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Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.

TL;DR: This study provides the first direct evidence that aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with essential hypertension.
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