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Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary

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TLDR
In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Abstract
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.

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2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC).

Giuseppe Mancia, +89 more
TL;DR: In this article, a randomized controlled trial of Aliskiren in the Prevention of Major Cardiovascular Events in Elderly people was presented. But the authors did not discuss the effect of the combination therapy in patients living with systolic hypertension.
Journal ArticleDOI

Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis.

TL;DR: Aortic stiffness expressed as aortic PWV is a strong predictor of future CV events and all-cause mortality and the predictive ability of arterial stiffness is higher in subjects with a higher baseline CV risk.
References
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Increased central pulse pressure and augmentation index in subjects with hypercholesterolemia

TL;DR: Patients with hypercholesterolemia have a higher central pulse pressure and stiffer blood vessels than matched controls, despite similar peripheral blood pressures, and assessment may improve risk stratification.
Journal ArticleDOI

Increased central artery stiffness in impaired glucose metabolism and type 2 diabetes: the Hoorn Study.

TL;DR: Impaired glucose metabolism (IGM) and type 2 diabetes (DM-2) are associated with high cardiovascular disease risk and increases in peripheral and central artery stiffness may represent pathophysiologic pathways through which glucose tolerance status leads to cardiovascular disease.
Journal ArticleDOI

Structural and Genetic Bases of Arterial Stiffness

TL;DR: Data concerning the heritability of arterial stiffness are reviewed, and an integrated view of the structural and genetic determinants of arterials stiffness is proposed, based on a candidate gene approach and recent studies on gene expression profile.
Journal ArticleDOI

Effect of Age on Brachial Artery Wall Properties Differs From the Aorta and Is Gender Dependent: A Population Study

TL;DR: The effect of age on large-artery wall properties is not uniform but depends on gender and vascular territory, and distensibility of the aorta, an elastic artery, decreases with age.
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