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Expert consensus document on arterial stiffness : methodological issues and clinical applications. Commentary

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TLDR
In this paper, the authors summarized the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.
Abstract
In recent years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. Indeed, the assessment of arterial stiffness is increasingly used in the clinical assessment of patients. Although several papers have previously addressed the methodological issues concerning the various indices of arterial stiffness currently available, and their clinical applications, clinicians and researchers still report difficulties in selecting the most appropriate methodology for their specific use. This paper summarizes the proceedings of several meetings of the European Network for Non-invasive Investigation of Large Arteries and is aimed at providing an updated and practical overview of the most relevant methodological aspects and clinical applications in this area.

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Early vascular aging and the role of central blood pressure.

TL;DR: The idea of early vascular aging, that is the acceleration of vascular aging seems to be a promising tool for clinical guidance in individuals at increased cardiovascular risk or a strong family history of early cardiovascular manifestations.
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Augmentation Index, Left Ventricular Contractility, and Wave Reflection

TL;DR: It is concluded that AIx is determined by chronotropic rather than inotropic effects, as well as factors other than wave reflection, as a result of arterial waveform changes in response to reduced “wave reflection” and increased left ventricular contractility induced by dobutamine.
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How to Measure Arterial Stiffness in Humans.

TL;DR: A brief review of methods in use, highly weighing their scrutiny and purity in quantifying arterial stiffness, rather than focusing on their ease of application or the level at which methods have demonstrated their prognostic and diagnostic potential.
Journal ArticleDOI

Numerical Validation of a New Method to Assess Aortic Pulse Wave Velocity from a Single Recording of a Brachial Artery Waveform with an Occluding Cuff

TL;DR: Simulations question the working principle of the Arteriograph, and data indicate that the method picks up wave reflection phenomena confined to the brachial artery, and derived values of PWV rather reflect the stiffness of the Brachial arteries.
Journal Article

Comparative study of methodologies for pulse wave velocity estimation. Commentary

TL;DR: In this paper, the authors compared the reliability of Complior and PulsePen devices in estimating PWV, while the Stiffness Index (Sl) determined by the PulseTrace device was found to be inappropriate as a surrogate of PWV.
References
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Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.

TL;DR: This study provides the first direct evidence that aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in patients with essential hypertension.
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