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Unified Parkinson's Disease Rating Scale

Victor R. Preedy, +1 more
- pp 4343-4343
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The article was published on 2010-01-01. It has received 691 citations till now. The article focuses on the topics: Unified Parkinson's disease rating scale.

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Journal ArticleDOI

The association between motor subtypes and psychopathology in Parkinson's disease.

TL;DR: This study shows that non-tremor-dominant PD is associated with cognitive deterioration, depression, apathy, and hallucinations, which has implications for future research into the pathophysiology of psychopathology in PD.
Journal ArticleDOI

Neurodegeneration Across Stages of Cognitive Decline in Parkinson Disease

TL;DR: Hippocampal atrophy is a biomarker of initial cognitive decline in PD, including impaired memory encoding and storage, suggesting heterogeneity in the neural substrate of memory impairment.
Journal ArticleDOI

Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial

TL;DR: A randomised, double-blind, placebo-controlled and active-controlled trial of opicapone as an adjunct to levodopa in patients with Parkinson's disease with end-of-dose motor fluctuations, finding that treatment with opiapone 50 mg was superior to placebo.
Journal ArticleDOI

Estimation of step-by-step spatio-temporal parameters of normal and impaired gait using shank-mounted magneto-inertial sensors: application to elderly, hemiparetic, parkinsonian and choreic gait

TL;DR: The proposed spatio-temporal parameters estimates showed smaller errors than those reported in previous studies and a similar level of precision and accuracy for both healthy and pathologic gait patterns, suggesting that the proposed method is suitable for routine clinical use.
Journal ArticleDOI

The Spectrum of Parkinsonian Manifestations Associated With Glucocerebrosidase Mutations

TL;DR: In the homozygous and heterozygous states, GBA mutations are associated with a spectrum of parkinsonian phenotypes ranging from Parkinson disease, mostly of the akinetic type, to a less common phenotype characteristic of Lewy body dementia.
References
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Journal ArticleDOI

Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.

Christopher G. Goetz, +87 more
- 15 Nov 2008 - 
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI

Colonic inflammation in Parkinson's disease.

TL;DR: Findings provide evidence that enteric inflammation occurs in Parkinson's disease and further reinforce the role of peripheral inflammation in the initiation and/or the progression of the disease.
Journal ArticleDOI

Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease

TL;DR: Although freezing of gait can be improved by low-frequency electrical stimulation of the pedunculopontine nucleus area in some patients with Parkinson's disease, the overall results are disappointing compared to the high levels of expectation raised by previous open label studies.
Journal ArticleDOI

The Clinically Important Difference on the Unified Parkinson's Disease Rating Scale

TL;DR: In this paper, a cross-sectional analysis of the CIDs for UPDRS total and motor scores was performed on patients with Parkinson disease (PD) using distribution-and anchor-based approaches based on the following external standards: disability (10% on the Schwab and England Activities of Daily Living Scale), disease stage (1 stage on the Hoehn and Yahr Scale), and quality of life (1 SD on the 12-Item Short Form Health Survey).