Book ChapterDOI
Unified Parkinson's Disease Rating Scale
Victor R. Preedy,Ronald R. Watson +1 more
- pp 4343-4343
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The article was published on 2010-01-01. It has received 691 citations till now. The article focuses on the topics: Unified Parkinson's disease rating scale.read more
Citations
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Journal ArticleDOI
The association between motor subtypes and psychopathology in Parkinson's disease.
TL;DR: This study shows that non-tremor-dominant PD is associated with cognitive deterioration, depression, apathy, and hallucinations, which has implications for future research into the pathophysiology of psychopathology in PD.
Journal ArticleDOI
Neurodegeneration Across Stages of Cognitive Decline in Parkinson Disease
Daniel Weintraub,Jimit Doshi,Deepthi Koka,Christos Davatzikos,Andrew Siderowf,John E. Duda,John E. Duda,David A. Wolk,Paul J. Moberg,Paul J. Moberg,Sharon X. Xie,Christopher M. Clark,Christopher M. Clark +12 more
TL;DR: Hippocampal atrophy is a biomarker of initial cognitive decline in PD, including impaired memory encoding and storage, suggesting heterogeneity in the neural substrate of memory impairment.
Journal ArticleDOI
Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial
Joaquim J. Ferreira,Andrew J. Lees,José-Francisco Rocha,Werner Poewe,Olivier Rascol,Patrício Soares-da-Silva,Patrício Soares-da-Silva +6 more
TL;DR: A randomised, double-blind, placebo-controlled and active-controlled trial of opicapone as an adjunct to levodopa in patients with Parkinson's disease with end-of-dose motor fluctuations, finding that treatment with opiapone 50 mg was superior to placebo.
Journal ArticleDOI
Estimation of step-by-step spatio-temporal parameters of normal and impaired gait using shank-mounted magneto-inertial sensors: application to elderly, hemiparetic, parkinsonian and choreic gait
Diana Trojaniello,Andrea Cereatti,Elisa Pelosin,Laura Avanzino,Anat Mirelman,Jeffrey M. Hausdorff,Jeffrey M. Hausdorff,Ugo Della Croce +7 more
TL;DR: The proposed spatio-temporal parameters estimates showed smaller errors than those reported in previous studies and a similar level of precision and accuracy for both healthy and pathologic gait patterns, suggesting that the proposed method is suitable for routine clinical use.
Journal ArticleDOI
The Spectrum of Parkinsonian Manifestations Associated With Glucocerebrosidase Mutations
TL;DR: In the homozygous and heterozygous states, GBA mutations are associated with a spectrum of parkinsonian phenotypes ranging from Parkinson disease, mostly of the akinetic type, to a less common phenotype characteristic of Lewy body dementia.
References
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Journal ArticleDOI
Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Christopher G. Goetz,Barbara C. Tilley,Stephanie R. Shaftman,Glenn T. Stebbins,Stanley Fahn,Pablo Martinez-Martin,Werner Poewe,Cristina Sampaio,Matthew B. Stern,Richard Dodel,Bruno Dubois,Robert G. Holloway,Joseph Jankovic,Jaime Kulisevsky,Anthony E. Lang,Andrew J. Lees,Sue Leurgans,Peter A. LeWitt,David L. Nyenhuis,C. Warren Olanow,Olivier Rascol,Anette Schrag,Jeanne A. Teresi,Jacobus J. van Hilten,Nancy R. LaPelle,Pinky Agarwal,Saima Athar,Yvette Bordelan,Helen Bronte-Stewart,Richard Camicioli,Kelvin L. Chou,Wendy Cole,Arif Dalvi,Holly Delgado,Alan Diamond,Jeremy P.R. Dick,John E. Duda,Rodger J. Elble,Carol Evans,V. G. H. Evidente,Hubert H. Fernandez,Susan H. Fox,Joseph H. Friedman,Robin D. Fross,David A. Gallagher,Deborah A. Hall,Neal Hermanowicz,Vanessa K. Hinson,Stacy Horn,Howard I. Hurtig,Un Jung Kang,Galit Kleiner-Fisman,Olga Klepitskaya,Katie Kompoliti,Eugene C. Lai,Maureen L. Leehey,Iracema Leroi,Kelly E. Lyons,Terry McClain,Steven W. Metzer,Janis M. Miyasaki,John C. Morgan,Martha Nance,Joanne Nemeth,Rajesh Pahwa,Sotirios A. Parashos,Jay S. Schneider,Kapil D. Sethi,Lisa M. Shulman,Andrew Siderowf,Monty Silverdale,Tanya Simuni,Mark Stacy,Robert Malcolm Stewart,Kelly L. Sullivan,David M. Swope,Pettaruse M. Wadia,Richard Walker,Ruth H. Walker,William J. Weiner,Jill Wiener,Jayne R. Wilkinson,Joanna M. Wojcieszek,Summer C. Wolfrath,Frederick Wooten,Allen Wu,Theresa A. Zesiewicz,Richard M. Zweig +87 more
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI
Neurostimulation for Parkinson's Disease with Early Motor Complications
W. M. M. Schuepbach,Jörn Rau,Karina Knudsen,Jens Volkmann,Paul Krack,Lars Timmermann,Thomas D. Hälbig,Helke Hesekamp,S. M. Navarro,Niklaus Meier,Daniela Falk,Maximilian Mehdorn,S. Paschen,Mohammad Maarouf,Michael T. Barbe,Gereon R. Fink,Andreas Kupsch,Doreen Gruber,G.-H. Schneider,Eric Seigneuret,Andrea Kistner,Patrick Chaynes,Fabienne Ory-Magne,C. Brefel Courbon,Jan Vesper,Alfons Schnitzler,Lars Wojtecki,Jean-Luc Houeto,Benoit Bataille,David Maltête,P. Damier,Sylvie Raoul,F. Sixel-Doering,D. Hellwig,Alireza Gharabaghi,Rejko Krüger,M. O. Pinsker,Florian Amtage,J. Regis,Tatiana Witjas,Stéphane Thobois,Patrick Mertens,Manja Kloss,Andreas Hartmann,Wolfgang H. Oertel,Bart Post,Hans Speelman,Yves Agid,Carmen Schade-Brittinger,Günther Deuschl +49 more
TL;DR: Subthalamic stimulation was superior to medical therapy in patients with Parkinson's disease and early motor complications and time with good mobility and no dyskinesia.
Journal ArticleDOI
Colonic inflammation in Parkinson's disease.
David Devos,Thibaud Lebouvier,Bernard Lardeux,Bernard Lardeux,Mandy Biraud,Tiphaine Rouaud,Tiphaine Rouaud,Hélène Pouclet,Emmanuel Coron,Stanislas Bruley des Varannes,Philippe Naveilhan,Philippe Naveilhan,Jean-Michel Nguyen,Michel Neunlist,Michel Neunlist,Pascal Derkinderen +15 more
TL;DR: Findings provide evidence that enteric inflammation occurs in Parkinson's disease and further reinforce the role of peripheral inflammation in the initiation and/or the progression of the disease.
Journal ArticleDOI
Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease
M.U. Ferraye,M.U. Ferraye,Bettina Debû,Bettina Debû,Valérie Fraix,Valérie Fraix,Laurent Goetz,Laurent Goetz,Claire Ardouin,Jérôme Yelnik,C. Henry-Lagrange,C. Henry-Lagrange,Eric Seigneuret,Brigitte Piallat,Brigitte Piallat,Paul Krack,Paul Krack,J.F. Le Bas,J.F. Le Bas,Alim-Louis Benabid,Alim-Louis Benabid,Stephan Chabardes,Stephan Chabardes,Pierre Pollak,Pierre Pollak +24 more
TL;DR: Although freezing of gait can be improved by low-frequency electrical stimulation of the pedunculopontine nucleus area in some patients with Parkinson's disease, the overall results are disappointing compared to the high levels of expectation raised by previous open label studies.
Journal ArticleDOI
The Clinically Important Difference on the Unified Parkinson's Disease Rating Scale
L. Shulman,Ann L. Gruber-Baldini,Karen E. Anderson,Paul S. Fishman,Stephen G. Reich,William J. Weiner +5 more
TL;DR: In this paper, a cross-sectional analysis of the CIDs for UPDRS total and motor scores was performed on patients with Parkinson disease (PD) using distribution-and anchor-based approaches based on the following external standards: disability (10% on the Schwab and England Activities of Daily Living Scale), disease stage (1 stage on the Hoehn and Yahr Scale), and quality of life (1 SD on the 12-Item Short Form Health Survey).