Gerardo Heiss

TL;DR: In this paper, the authors combine cognitive and genetic data from the CHARGE and COGENT consortia, and UK Biobank (total N = 300,486; age 16-102) and find 148 genome-wide significant independent loci associated with general cognitive function.

TL;DR: Results provide the first indication that periodontitis may play a role in the pathogenesis of atheroma formation, as well as in cardiovascular events, in patients aged 52 to 75 years.

TL;DR: Overall, the plasma triglyceride level showed no independent association with coronary mortality, but in subgroups of subjects with lower HDL and LDL cholesterol levels and in younger subjects, defined a priori, an association was observed, although this association was small and was not statistically significant after an adjustment for the plasma glucose level.

TL;DR: The findings reinforce the utility of major, modifiable risk factor assessment to identify individuals at risk for CHD for preventive action and suggest that routine measurement of these novel markers is not warranted for risk assessment.

TL;DR: In this article, the authors used 1000 Genomes Project-imputed genotype data in up to ∼370,000 women to identify 389 independent signals (P < 5 × 10-8) for age at menarche, a milestone in female pubertal development.