N
Nilesh J. Samani
Researcher at University of Leicester
Publications - 836
Citations - 127518
Nilesh J. Samani is an academic researcher from University of Leicester. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 149, co-authored 779 publications receiving 113545 citations. Previous affiliations of Nilesh J. Samani include University Hospitals of Leicester NHS Trust & Glenfield Hospital.
Papers
More filters
Journal ArticleDOI
Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure
George Markousis-Mavrogenis,Waldemar B. Minich,Ali A. Al-Mubarak,Stefan D. Anker,John G.F. Cleland,Kenneth Dickstein,Chim C. Lang,Leong L. Ng,Nilesh J. Samani,Faiez Zannad,Marco Metra,Petra Seemann,Antonia Hoeg,Patricio Lopez,Dirk J. van Veldhuisen,W. De Boer,Adriaan A. Voors,P. Van Der Meer,Lutz Schomburg,Nils Bomer +19 more
TL;DR: In this paper , the authors investigated the prevalence and clinical/prognostic associations of four AABs recognizing the M2-muscarinic receptor or the β1-, β2-, or β3-adrenergic receptor in a large and well-characterized cohort of patients with heart failure.
Posted ContentDOI
Identification and Characterization of novel long non-coding RNAs in vascular smooth cells
Charles U. Solomon,David G. McVey,Catherine Andreadi,Peng Gong,Lanka Turner,Sonja Khemiri,Julie C. Chamberlain,Tom R. Webb,Nilesh J. Samani,Shu Ye +9 more
TL;DR: In this paper , the authors identify and characterize the lncRNA landscape of vascular smooth muscle cells (VSMC) using an ensemble of bioinformatics tools to identify 329 novel lncRNAs from a large VSMC RNA-Seq dataset.
Posted ContentDOI
Association of leucocyte telomere length with frailty: a large-scale cross-sectional analysis in UK Biobank
Bountziouka,Christopher P. Nelson,Codd,Qingning Wang,Crispin Musicha,Elias Allara,Stephen Kaptoge,Di Angelantonio E,Adam S. Butterworth,Thompson,Elizabeth M Curtis,Angela M. Wood,John Danesh,Nicholas C. Harvey,Cyrus Cooper,Nilesh J. Samani +15 more
TL;DR: In this article, a large-scale population-based study, involving over 441,000 participants, provides strong evidence that shorter leucocyte telomere length is associated with higher risk of both pre-frailty and frailty.
Journal ArticleDOI
Reply to the Letter by Hayashi et al
Wibke Reinhard,Bernhard M. Kaess,Radoslaw Debiec,Christopher P. Nelson,Klaus Stark,Martin D. Tobin,Peter W. Macfarlane,Maciej Tomaszewski,Nilesh J. Samani,Christian Hengstenberg +9 more
TL;DR: The differentiation between the notching and slurring type of early repolarization (ER) can sometimes be difficult, and the lack of a clear definition of notching or slurring has already been highlighted, but in the present study this distinction is made.
Journal ArticleDOI
Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation
David Adlam,Takiy Berrandou,Adrien Georges,Christopher P. Nelson,Eleni Giannoulatou,Josephine Henry,Lijiang Ma,Montgomery Blencowe,Tamiel N. Turley,Min-Lee Yang,Sandesh Chopade,Chris Finan,Peter S. Braund,I. Sadeg-Sayoud,Siiri E. Iismaa,Matthew L. Kosel,Xiang Zhou,Stephen E. Hamby,Jenny S. Cheng,Lu Liu,I. Tarr,David W.M. Muller,Valentina d'Escamard,Annette King,Liam R. Brunham,A. Baranowska-Clarke,Stéphanie Debette,Philippe Amouyel,Jeffrey W. Olin,Snehal Patil,Stephanie Hesselson,Keerat Junday,Stavroula Kanoni,Krishna G. Aragam,Adam S. Butterworth,Mark K Bakker,Ynte M. Ruigrok,Marysia S. Tweet,Rajiv Gulati,Nicolas Combaret,Daniella Kadian-Dodov,Jonathan M. Kalman,Diane Fatkin,Aroon D. Hingorani,Jacqueline Saw,Tom R. Webb,Sharonne N. Hayes,Xia Yang,Santhi K. Ganesh,Timothy M. Olson,Jason C. Kovacic,Robert M. Graham,Nilesh J. Samani,Nabila Bouatia-Naji +53 more
TL;DR: In this article , a genome-wide association meta-analysis (1,917 cases and 9,292 controls) identifying 16 risk loci for spontaneous coronary artery dissection (SCAD) is presented.