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Nilesh J. Samani
Researcher at University of Leicester
Publications - 836
Citations - 127518
Nilesh J. Samani is an academic researcher from University of Leicester. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 149, co-authored 779 publications receiving 113545 citations. Previous affiliations of Nilesh J. Samani include University Hospitals of Leicester NHS Trust & Glenfield Hospital.
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Journal ArticleDOI
Myocyte stress 1 plays an important role in cellular hypertrophy and protection against apoptosis
TL;DR: Findings suggest the involvement of MS1 in cellular hypertrophy and protection against apoptosis in striated muscle actin‐binding protein.
Journal ArticleDOI
Evaluation of the uptake and delivery of the NHS Health Check programme in England, using primary care data from 9.5 million people: a cross-sectional study.
Riyaz S. Patel,Sharmani Barnard,Katherine Thompson,Catherine Lagord,Emma Clegg,Robert Worrall,Tim J. Evans,Slade Carter,Julian Flowers,Dave Roberts,Michaela Nuttall,Nilesh J. Samani,Nilesh J. Samani,John Robson,Matt Kearney,John E. Deanfield,Jamie Waterall +16 more
TL;DR: A national analysis of the NHSHC programme, using primary care data from over 9.5 million individuals offered a check, reveals an uptake rate of over 50% and no significant evidence of inequity by ethnicity or deprivation.
Journal Article
Common variants at 10 genomic loci influence hemoglobin A1C levels via glycemic and nonglycemic pathways (Diabetes (2010) 59, (3229-3239))
Nicole Soranzo,Serena Sanna,Eleanor Wheeler,Christian Gieger,Dörte Radke,Josée Dupuis,Nabila Bouatia-Naji,Claudia Langenberg,Inga Prokopenko,Elliot S. Stolerman,Manjinder S. Sandhu,Matthew M. Heeney,Joseph M. Devaney,Muredach P. Reilly,Sally L. Ricketts,Alexandre F.R. Stewart,Benjamin F. Voight,Christina Willenborg,Benjamin J. Wright,David Altshuler,Dan E. Arking,Beverley Balkau,Daniel R. Barnes,Eric Boerwinkle,Bernhard O. Böhm,Amélie Bonnefond,Lori L. Bonnycastle,Dorret I. Boomsma,Stefan R. Bornstein,Yvonne Böttcher,Suzannah Bumpstead,Mary Susan Burnett-Miller,Harry Campbell,Antonio Cao,John C. Chambers,Robert Clark,Francis S. Collins,Josef Coresh,Eco J. C. de Geus,Mariano Dei,Panos Deloukas,Angela Döring,Josephine M. Egan,Roberto Elosua,Luigi Ferrucci,Nita G. Forouhi,Caroline S. Fox,Christopher S. Franklin,Maria Grazia Franzosi,Sophie Gallina,Anuj Goel,J. Graessler,Harald Grallert,Andreas Greinacher,David Hadley,Alistair S. Hall,Anders Hamsten,Caroline Hayward,Simon Heath,Christian Herder,Georg Homuth,Jouke-Jan Hottenga,Rachel Hunter-Merrill,Thomas Illig,Anne U. Jackson,Antti Jula,Marcus E. Kleber,Christopher W. Knouff,Augustine Kong,Jaspal S. Kooner,Anna Köttgen,Peter Kovacs,Knut Krohn,Brigitte Kühnel,Johanna Kuusisto,Markku Laakso,Mark Lathrop,Cécile Lecoeur,Man Li,Mingyao Li,Ruth J. F. Loos,Jian'an Luan,Valeriya Lyssenko,Reedik Mägi,Patrik K. E. Magnusson,Anders Mälarstig,Massimo Mangino,María Teresa Martínez-Larrad,Winfried März,Wendy L. McArdle,Ruth McPherson,Christa Meisinger,Thomas Meitinger,Olle Melander,Karen L. Mohlke,Vincent Mooser,Mario A. Morken,Narisu Narisu,David M. Nathan,Matthias Nauck,Christopher J. O'Donnell,Konrad Oexle,Nazario Olla,James S. Pankow,Felicity Payne,John F. Peden,Nancy L. Pedersen,Leena Peltonen,Markus Perola,Markus Perola,Ozren Polasek,Eleonora Porcu,Daniel J. Rader,Wolfgang Rathmann,Samuli Ripatti,Samuli Ripatti,Ghislain Rocheleau,Michael Roden,Igor Rudan,Veikko Salomaa,Richa Saxena,David Schlessinger,Heribert Schunkert,Peter Schwarz,Udo Seedorf,Elizabeth Selvin,Manuel Serrano-Ríos,Peter Shrader,Angela Silveira,David S. Siscovick,Kjioung Song,Tim D. Spector,Kari Stefansson,Valgerdur Steinthorsdottir,David P. Strachan,Rona J. Strawbridge,Michael Stumvoll,Ida Surakka,Ida Surakka,Amy J. Swift,Toshiko Tanaka,Alexander Teumer,Gudmar Thorleifsson,Unnur Thorsteinsdottir,Anke Tönjes,Gianluca Usala,Veronique Vitart,Henry Völzke,Henri Wallaschofski,Dawn M. Waterworth,Hugh Watkins,H.-Erich Wichmann,Sarah H. Wild,Gonneke Willemsen,Gordon H. Williams,James F. Wilson,Juliane Winkelmann,Alan F. Wright,Carina Zabena,Jing Hua Zhao,Stephen E. Epstein,Jeanette Erdmann,Hakon Hakonarson,Sekar Kathiresan,Kay-Tee Khaw,Robert Roberts,Nilesh J. Samani,Mark D. Fleming,Robert Sladek,Gonçalo R. Abecasis,Michael Boehnke,Philippe Froguel,Leif Groop,Mark I. McCarthy,W. H. Linda Kao,Jose C. Florez,Manuela Uda,Nicholas J. Wareham,Inês Barroso,James B. Meigs +179 more
TL;DR: This article calculated net reclassification of diabetes mellitus patients using a database of patients diagnosed with type 2 diabetes over a 12-month period and found that the number of patients with diabetes decreases with age and disease progression.
Journal ArticleDOI
Proteomic diversity of high-density lipoprotein explains its association with clinical outcome in patients with heart failure.
Johanna E. Emmens,Donald J. L. Jones,Thong Huy Cao,Daniel C. S. Chan,Simon P. R. Romaine,Paulene A. Quinn,Stefan D. Anker,Stefan D. Anker,John G.F. Cleland,Kenneth Dickstein,Kenneth Dickstein,Gerasimos Filippatos,Hans L. Hillege,Chim C. Lang,Piotr Ponikowski,Nilesh J. Samani,Dirk J. van Veldhuisen,F. Zannad,Aeilko H. Zwinderman,Marco Metra,Rudolf A. de Boer,Adriaan A. Voors,Leong L. Ng +22 more
TL;DR: An in‐depth investigation of the multifunctional HDL proteome is performed to reveal underlying pathophysiological mechanisms explaining the association between HDL and clinical outcome.
Journal ArticleDOI
Increased expression of the SA gene in the kidney of the spontaneously hypertensive rat is localized to the proximal tubule.
TL;DR: The localization of the increased expression of the SA gene in the SHR kidney compared with the WKY rat kidney to the proximal tubule suggests that it might influence blood pressure through effects on tubular function.