École Polytechnique Fédérale de Lausanne

About: École Polytechnique Fédérale de Lausanne is a facility organization based out in Lausanne, Switzerland. It is known for research contribution in the topics: Population & Catalysis. The organization has 44041 authors who have published 98296 publications receiving 4372092 citations. The organization is also known as: EPFL & ETHL.

Model transformation: the heart and soul of model-driven software development

Abstract: The model-driven approach can increase development productivity and quality by describing important aspects of a solution with human-friendly abstractions and by generating common application fragments with templates. This article examines different approaches to model transformations and recommends desirable language characteristics for describing them.

LIFT: Learned Invariant Feature Transform

Abstract: We introduce a novel Deep Network architecture that implements the full feature point handling pipeline, that is, detection, orientation estimation, and feature description. While previous works have successfully tackled each one of these problems individually, we show how to learn to do all three in a unified manner while preserving end-to-end differentiability. We then demonstrate that our Deep pipeline outperforms state-of-the-art methods on a number of benchmark datasets, without the need of retraining.

H0LiCOW – XIII. A 2.4 per cent measurement of H0 from lensed quasars: 5.3σ tension between early- and late-Universe probes

Abstract: We present a measurement of the Hubble constant ($H_{0}$) and other cosmological parameters from a joint analysis of six gravitationally lensed quasars with measured time delays. All lenses except the first are analyzed blindly with respect to the cosmological parameters. In a flat $\Lambda$CDM cosmology, we find $H_{0} = 73.3_{-1.8}^{+1.7}$, a 2.4% precision measurement, in agreement with local measurements of $H_{0}$ from type Ia supernovae calibrated by the distance ladder, but in $3.1\sigma$ tension with $Planck$ observations of the cosmic microwave background (CMB). This method is completely independent of both the supernovae and CMB analyses. A combination of time-delay cosmography and the distance ladder results is in $5.3\sigma$ tension with $Planck$ CMB determinations of $H_{0}$ in flat $\Lambda$CDM. We compute Bayes factors to verify that all lenses give statistically consistent results, showing that we are not underestimating our uncertainties and are able to control our systematics. We explore extensions to flat $\Lambda$CDM using constraints from time-delay cosmography alone, as well as combinations with other cosmological probes, including CMB observations from $Planck$, baryon acoustic oscillations, and type Ia supernovae. Time-delay cosmography improves the precision of the other probes, demonstrating the strong complementarity. Allowing for spatial curvature does not resolve the tension with $Planck$. Using the distance constraints from time-delay cosmography to anchor the type Ia supernova distance scale, we reduce the sensitivity of our $H_0$ inference to cosmological model assumptions. For six different cosmological models, our combined inference on $H_{0}$ ranges from $\sim73$-$78~\mathrm{km~s^{-1}~Mpc^{-1}}$, which is consistent with the local distance ladder constraints.

Genomics and the origin of species

Abstract: Speciation is a fundamental evolutionary process, the knowledge of which is crucial for understanding the origins of biodiversity. Genomic approaches are an increasingly important aspect of this research field. We review current understanding of genome-wide effects of accumulating reproductive isolation and of genomic properties that influence the process of speciation. Building on this work, we identify emergent trends and gaps in our understanding, propose new approaches to more fully integrate genomics into speciation research, translate speciation theory into hypotheses that are testable using genomic tools and provide an integrative definition of the field of speciation genomics.