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Institution

Kyoto University

EducationKyoto, Japan
About: Kyoto University is a education organization based out in Kyoto, Japan. It is known for research contribution in the topics: Catalysis & Population. The organization has 85837 authors who have published 217215 publications receiving 6526826 citations. The organization is also known as: Kyōto University & Kyōto daigaku.
Topics: Catalysis, Population, Gene, Transplantation, Ion


Papers
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Journal ArticleDOI
TL;DR: Hydrogels with two different types of carboxyl group locations were employed as substrates containing the carboxylic acid, while ethylenediamine and benzylamine were used as amine to study the mechanism of amide formation between carboxYlic acid and amine in aqueous media using 1-ethyl-3-(3-(dimethylamino)propyl)carbodiimide hydrochloride.

707 citations

Book
25 Mar 1988
TL;DR: In this article, the authors present a resource allocation approach for resource allocation problems in the ORS problem, using an algorithm based approach, which they call Algorithmic Approaches.
Abstract: (1989). Resource Allocation Problems: Algorithmic Approaches. Journal of the Operational Research Society: Vol. 40, No. 7, pp. 701-702.

705 citations

Journal ArticleDOI
TL;DR: New self-organizing aspects of human corticogenesis are shown: spontaneous development of intracortical polarity, curving morphology, and complex zone separations, which suggest human neocorticogenesis involves intrinsic programs that enable the emergence of complex neocortical features.
Abstract: Here, using further optimized 3D culture that allows highly selective induction and long-term growth of human ES cell (hESC)-derived cortical neuroepithelium, we demonstrate unique aspects of self-organization in human neocorticogenesis. Self-organized cortical tissue spontaneously forms a polarity along the dorsocaudal-ventrorostral axis and undergoes region-specific rolling morphogenesis that generates a semispherical structure. The neuroepithelium self-forms a multilayered structure including three neuronal zones (subplate, cortical plate, and Cajal-Retzius cell zones) and three progenitor zones (ventricular, subventricular, and intermediate zones) in the same apical-basal order as seen in the human fetal cortex in the early second trimester. In the cortical plate, late-born neurons tend to localize more basally to early-born neurons, consistent with the inside-out pattern seen in vivo. Furthermore, the outer subventricular zone contains basal progenitors that share characteristics with outer radial glia abundantly found in the human, but not mouse, fetal brain. Thus, human neocorticogenesis involves intrinsic programs that enable the emergence of complex neocortical features.

704 citations

Journal ArticleDOI
TL;DR: A novel method to introduce DNA into in/exo utero embryonic mouse brains at various stages by using electroporation, which will be a powerful tool to characterize gene function in various settings due to its high efficiency and localized gene expression.

702 citations

Journal ArticleDOI
TL;DR: The K2K experiment observed indications of neutrino oscillation after 250 km flight of υμ. as mentioned in this paper The observed number of events in the data corresponding to 4.8 x 1019 protons on target is 56, while 80.1 5.4 + 6.2 is expected.
Abstract: The K2K experiment observed indications of neutrino oscillation after 250 km flight of υμ. The observed number of events in the data corresponding to 4.8 x 1019 protons on target is 56, while 80.1 5.4 +6.2 is expected. Both the decrease of the events and observed spectrum shape distortion are consistent with neutrino oscillation. The probability that the observations are statistical fluctuation of non oscillation is less than 1%. The allowed region of oscillation parameters is consistent with the one obtained from the atmospheric neutrino observation. After the accident of Super-Kamiokande (SK) detector, the reconstruction of SK has finished in 2002 and the K2K experiment resumed in December 2002.

702 citations


Authors

Showing all 86225 results

NameH-indexPapersCitations
Kari Alitalo174817114231
Ralph M. Steinman171453121518
Masayuki Yamamoto1711576123028
Karl Deisseroth160556101487
Kenji Kangawa1531117110059
Takashi Taniguchi1522141110658
Ben Zhong Tang1492007116294
Takeo Kanade147799103237
Yuji Matsuzawa143836116711
Tasuku Honjo14171288428
Kenneth M. Yamada13944672136
Y. B. Hsiung138125894278
Shuh Narumiya13759570183
Kevin P. Campbell13752160854
Junji Tojo13587884615
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023234
2022679
20218,533
20208,740
20198,050
20187,932