Institution
University of California
Education•Oakland, California, United States•
About: University of California is a education organization based out in Oakland, California, United States. It is known for research contribution in the topics: Population & Layer (electronics). The organization has 55175 authors who have published 52933 publications receiving 1491169 citations. The organization is also known as: UC & University of California System.
Topics: Population, Layer (electronics), Cancer, Context (language use), Gene
Papers published on a yearly basis
Papers
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20 Nov 1992TL;DR: In this article, a method for attaching semiconductor nanocrystals to solid inorganic surfaces, using self-assembled bifunctional organic monolayers as bridge compounds, is described.
Abstract: Methods are described for attaching semiconductor nanocrystals to solid inorganic surfaces, using self-assembled bifunctional organic monolayers as bridge compounds. Two different techniques are presented. One relies on the formation of self-assembled monolayers on these surfaces. When exposed to solutions of nanocrystals, these bridge compounds bind the crystals and anchor them to the surface. The second technique attaches nanocrystals already coated with bridge compounds to the surfaces. Analyses indicate the presence of quantum confined clusters on the surfaces at the nanolayer level. These materials allow electron spectroscopies to be completed on condensed phase clusters, and represent a first step towards synthesis of an organized assembly of clusters. These new products are also disclosed.
235 citations
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22 Oct 2007
TL;DR: This work presents an identity-and lighting-invariant system to estimate a driver's head pose, which is fully autonomous and operates online in daytime and nighttime driving conditions, using a monocular video camera sensitive to visible and near-infrared light.
Abstract: Recognizing driver awareness is an important prerequisite for the design of advanced automotive safety systems. Since visual attention is constrained to a driver's field of view, knowing where a driver is looking provides useful cues about his activity and awareness of the environment. This work presents an identity-and lighting-invariant system to estimate a driver's head pose. The system is fully autonomous and operates online in daytime and nighttime driving conditions, using a monocular video camera sensitive to visible and near-infrared light. We investigate the limitations of alternative systems when operated in a moving vehicle and compare our approach, which integrates Localized Gradient Orientation histograms with support vector machines for regression. We estimate the orientation of the driver's head in two degrees-of-freedom and evaluate the accuracy of our method in a vehicular testbed equipped with a cinematic motion capture system.
235 citations
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TL;DR: The proper use of pesticide chemicals must be based on an understanding of the behavior of the chemicals as they interact with air, water, soil, and biota, react or degrade, and migrate.
Abstract: Pesticides play an important role in maintaining agricultural productivity, but they may also be causes of contamination of air, water, soil, and food, with possible adverse effects on human and animal health. The proper use of pesticide chemicals must be based on an understanding of the behavior of the chemicals as they interact with air, water, soil, and biota, react or degrade, and migrate. This behavior is strongly influenced by the chemicals’ physical-chemical properties of solubility in water, vapor pressure or volatility, and tendency to sorb to organic and mineral matter in the soil.
235 citations
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TL;DR: Substantial delays before achieving cerebral "neuronal adequacy" appear to be required for eliciting a sensory experience, including the demonstration that a cortical stimulus can retroactively modify a skin-induced sensation even when C stimulus begins up to 500 msec after S stimulus.
Abstract: Some features of cerebral neuronal functions that are uniquely related to generation of conscious sensory responses, have been discovered. Included are two temporal factors: (1) Substantial delays, of up to about 0.5 sec, before achieving cerebral “ neuronal adequacy“ appear to be required for eliciting a sensory experience. This includes the demonstration that a cortical stimulus (C) can retroactively modify a skin (S)-induced sensation even when C stimulus begins up to 500 msec after S stimulus. (2) However, there appears to be a subjective referral of the experience back to the time of the cortical primary evoked response to S; subjectively the skin sensation would thus appear to have no delay. Stimuli that are inadequate for eliciting conscious sensory experience can nevertheless evoke considerable neuronal activity, including that represented in direct cortical responses or in primary (early) components of evoked potentials. Virtually all the qualities of somatic sensation (except pain) can be elicited by stimuli at postcentral gyrus, when intensities of suitable trains of pulses are kept down to liminal levels. Some additional implications, for the manner in which mental and neural events are related, are discussed.
235 citations
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TL;DR: The use of model-driven analysis of multiple data types relevant to transcriptional regulation of metabolism to discover novel regulatory mechanisms in Saccharomyces cerevisiae and the ability of an integrated metabolic and regulatory network model to predict growth phenotypes of transcription factor knockout strains are described.
Abstract: We describe the use of model-driven analysis of multiple data types relevant to transcriptional regulation of metabolism to discover novel regulatory mechanisms in Saccharomyces cerevisiae. We have reconstructed the nutrient-controlled transcriptional regulatory network controlling metabolism in S. cerevisiae consisting of 55 transcription factors regulating 750 metabolic genes, based on information in the primary literature. This reconstructed regulatory network coupled with an existing genome-scale metabolic network model allows in silico prediction of growth phenotypes of regulatory gene deletions as well as gene expression profiles. We compared model predictions of gene expression changes in response to genetic and environmental perturbations to experimental data to identify potential novel targets for transcription factors. We then identified regulatory cascades connecting transcription factors to the potential targets through a systematic model expansion strategy using published genome-wide chromatin immunoprecipitation and binding-site-motif data sets. Finally, we show the ability of an integrated metabolic and regulatory network model to predict growth phenotypes of transcription factor knockout strains. These studies illustrate the potential of model-driven data integration to systematically discover novel components and interactions in regulatory and metabolic networks in eukaryotic cells.
234 citations
Authors
Showing all 55232 results
Name | H-index | Papers | Citations |
---|---|---|---|
Meir J. Stampfer | 277 | 1414 | 283776 |
George M. Whitesides | 240 | 1739 | 269833 |
Michael Karin | 236 | 704 | 226485 |
Fred H. Gage | 216 | 967 | 185732 |
Rob Knight | 201 | 1061 | 253207 |
Martin White | 196 | 2038 | 232387 |
Simon D. M. White | 189 | 795 | 231645 |
Scott M. Grundy | 187 | 841 | 231821 |
Peidong Yang | 183 | 562 | 144351 |
Patrick O. Brown | 183 | 755 | 200985 |
Michael G. Rosenfeld | 178 | 504 | 107707 |
George M. Church | 172 | 900 | 120514 |
David Haussler | 172 | 488 | 224960 |
Yang Yang | 171 | 2644 | 153049 |
Alan J. Heeger | 171 | 913 | 147492 |