University of Veterinary Science

About: University of Veterinary Science is a education organization based out in Pyinmana, Myanmar. It is known for research contribution in the topics: Population & Receptor. The organization has 597 authors who have published 650 publications receiving 14262 citations.

Pathomorphological changes caused by T-2 trichothecene fusariotoxin in geese.

Abstract: T-2 trichothecene fusariotoxin was administered to 110 laying geese and 33 ganders in the active egg production period through a tube at 2-day intervals on a total of 10 occasions. After the treatment, the geese were subjected to detailed pathomorphological examination. In the ovaries of layers, a cessation of follicle maturation and follicle degeneration dependent on the toxin dose were observed, accompanied by ovulation and consequent peritonitis in the birds that died and in some of those killed by bleeding. Additional findings included involution of the oviduct, lymphocyte depletion, necrosis and amyloidosis in the spleen, catarrhal enteritis, signs of colloid stasis in the thyroid and large numbers of secretory granules in the cytoplasm of the adrenaline-producing cells of the adrenal gland. In the ganders, toxin administration did not reduce the intensity of spermatogenesis but in the spleen, intestine and endocrine glands it caused changes similar to those seen in the layers.

Evaluation of blood lipid peroxidation parameters in carbon tetrachloride (CCl4) toxicity in sheep.

Abstract: Seven female, 2-year-old, nonpregnant, Merino ewes were treated with a nonlethal dose of 0.3 ml/kg body mass carbon tetrachloride (CCl4) in 1:1 v/v dilution with paraffin oil via a stomach tube into the rumen. Blood samples were collected one day before and on the first, second, third, seventh and tenth day after toxin exposure to study the changes of the lipid peroxidation (LP) status of red blood cell haemolyzate (RBC-haem). The severity of liver damage was monitored by determination of aspartate aminotransferase (AST) activity and bilirubin concentration in the blood plasma. Twenty-four h after CCl4 exposure all animals became lethargic and anorexic, their heart rate and respiratory rate increased. On the subsequent two days these signs became more severe, but by the 10th day the symptoms disappeared. On the 1st and 2nd day following CCl4 exposure the concentration of malondialdehyde (MDA)--an end product of LP--in RBC-haem significantly increased. A slight decrease was found on the 3rd, 7th and 10th day, but MDA values remained significantly higher than the basal ones. The activity of glutathione peroxidase (GPX) in RBC-haem increased slowly on the 1st and 2nd day, then it rose intensively on the third day. GPX activity remained elevated until the 7th day, but on the 10th day it dropped again. Catalase (Cat) activity in RBC-haem did not show any significant changes during the experiment. AST activity in blood plasma showed a two-fold increase in the first three days; later on the high values decreased. Total and direct plasma bilirubin concentration slightly increased on the 3rd day, then both decreased. LP effects in CCl4-induced hepatocellular injury were significant in sheep, in line with the results of experiments on other species such as rats. The LP effects were demonstrated by the elevated MDA concentration and GPX activity.

Ultrasonographic findings of renal dysplasia in cocker spaniels: eight cases.

Abstract: A retrospective study of eight young Cocker Spaniels aged 9-24 months was performed to describe the ultrasonographic findings of histologically confirmed renal dysplasia Ultrasonography revealed kidneys of significantly (p < 0001) reduced volume in all dogs During qualitative evaluation, two different types of sonographic alterations could be seen In one type of the ultrasound alterations, corticomedullary demarcation was distinct and the renal cortex was remarkably thin, which was best seen in the dorsal (frontal) imaging plane In the other type of the ultrasound appearance, overall increased echogenicity with poor corticomedullary demarcation was noticed, and the kidneys could hardly be separated from their surroundings These features were best recognised in the sagittal (coronal) imaging plane In one dog with secondary hypercalcaemia, a hyperechoic corticomedullary area was also seen Post-mortem histological diagnosis revealed renal dysplasia and secondary fibrosis Based on ultrasound findings alone, renal dysplasia (renal familial disease) can be suspected when small kidneys with thin echogenic cortex are present in young dogs An ultrasound image, similar to that of fibrotic kidneys (increased overall echogenicity and reduced corticomedullary definition) cannot be differentiated from chronic inflammatory disease and from end-stage kidneys Therefore, ultrasound-guided biopsy or post-mortem histology is necessary for the definitive diagnosis of renal dysplasia This is the first study reporting on the ultrasound appearance of renal dysplasia in Cocker Spaniel dogs

Occurrence of some viruses and bacteria involved in respiratory diseases of ruminants in Hungary.

Abstract: Serological surveys, virological and bacteriological investigations were carried out on large populations of lambs and calves kept in intensive fattening units on Hungarian large-scale farms, in order to study the occurrence of viruses and bacteria involved in the respiratory disease complex. The investigations were carried out in stocks where 5-20% of the young animals succumbed to acute or chronic pneumonia every year. Serological surveys revealed that seropositivity to bovine adenovirus type 2 (BAV-2) and parainfluenza type 3 (PI-3) were the most widespread viral infections both in cattle and sheep (BAV-2: 56% and 88%, PI-3: 76% and 41%, respectively). Antibodies against infectious bovine rhinotracheitis virus (BHV-1) were also found in a high proportion (45%) of sera of 3-8 month old calves, while in 2-6 month old lambs ovine adenovirus 1 (OAV-1) was the third most frequent virus (22%). Bacteriological investigations demonstrated secondary infections caused by different Pasteurella haemolytica and Pasteurella multocida serotypes in most cases. In cattle herds P. multocida A proved to be the predominant bacterium: it was isolated in each herd examined, while P. haemolytica A1 strains were isolated in 7 and Haemophilus somnus in 2 out of 13 herds. In sheep flocks P. haemolytica was the most frequent species isolated, 10 serotypes were cultured from pneumonic sheep but serotypes A2, A1 and A8 were the dominant ones.