Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Construction of 6-thioguanine and 6-mercaptopurine carriers based on βcyclodextrins and gold nanoparticles
Rodrigo Sierpe,Michael Noyong,Ulrich Simon,Daniel Aguayo,Jaime Huerta,Marcelo J. Kogan,Nicolás Yutronic +6 more
TL;DR: This modification increased their solubility and improved their stability, betting by a site-specific transport due to their nanometric dimensions, among other advantages, and the in vitro permeability of the ternary systems was studied.
Journal ArticleDOI
Mechanically interlocked polymers based on rotaxanes.
TL;DR: In this article , the authors outline the synthetic strategies, structure-property relationships, and application explorations of various polyrotaxanes, including linear poly-rotaxane, poly-poly-axane networks, and rotaxane dendrimers.
Journal ArticleDOI
Differential Metal Ion Sensing by an Antipyrine Derivative in Aqueous and β-Cyclodextrin Media: Selectivity Tuning by β-Cyclodextrin.
Govindaraj Tamil Selvan,Sumathi Poomalai,Sivaraj Ramasamy,Paulraj Mosae Selvakumar,Israel V.M.V. Enoch,Sara Gràcia Lanas,Andrea Melchior +6 more
TL;DR: This is the first report of selectivity of two different cations by a chemosensor in water and in β-CD, and the antipyrine-cyclodextrin complex is optimized by two-dimensional rotating-frame Overhauser effect spectroscopy.
Journal ArticleDOI
Supramolecular systems based on calix[4]resorcine with mono-, di-, and tetracationic surfactants: Synergetic structural and solubilization behavior
Tatiana N. Pashirova,Аlbina Yu Ziganshina,Elza D. Sultanova,Svetlana S. Lukashenko,Yuliana R. Kudryashova,Elena P. Zhiltsova,Lucia Ya. Zakharova,Alexander I. Konovalov +7 more
TL;DR: In this paper, the formation of mixed structures of calix[4]resorcine with cationic surfactants has been found to proceed at the lower concentrations as compared to single CR solutions.
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A styryl based fluorogenic probe with high affinity for a cyclodextrin derivative.
Goutam Chakraborty,Goutam Chakraborty,Alok K. Ray,Alok K. Ray,Prabhat K. Singh,Prabhat K. Singh,Haridas Pal,Haridas Pal +7 more
TL;DR: A styryl-based fluorogenic probe is reported which registers a very high binding affinity with the sulfobutylether substituted β-CD, attributed to the strong electrostatic interactions between the cationic guest and the polyanionic host along with improved hydrophobic interactions due to the extended butylether groups present on the rims of the cyclodextrin cavity.
References
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Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
Journal ArticleDOI
Complexation Thermodynamics of Cyclodextrins.
Journal ArticleDOI
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
Journal ArticleDOI
Cyclodextrin Drug Carrier Systems.
Journal ArticleDOI
Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.