Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Two Gelation Mechanisms of Deoxycholate with Inorganic Additives: Hydrogen Bonding and Electrostatic Interactions.
TL;DR: This work describes the gelation behaviors of a biological amphiphile, deoxycholate (DC(-)), in aqueous solution by adding inorganic salts and modulating pH, and shows that electrostatic interaction and hydrogen bonding can separately act as the controlling interaction for the hydrogel formation.
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In vitro evaluation of drug release and antibacterial activity of a silver-loaded wound dressing coated with a multilayer system
Alejandra Mogrovejo-Valdivia,Oumaira Rahmouni,Nicolas Tabary,Mickaël Maton,Christel Neut,Bernard Martel,Nicolas Blanchemain +6 more
TL;DR: The utility of the intermediate thermal treatment step in the reduction of silver leakage in the polyelectrolyte solutions used in the L-b-L process is demonstrated and silver adsorption on the preliminary thermofixed layers did not affect the PEM system build-up.
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Stimulus-Responsive Supramolecular Host-Guest Assembly of a Cationic Pyrene Derivative with Sulfated β-Cyclodextrin.
Gaurav Singh,Prabhat K. Singh +1 more
TL;DR: This monomer-dimer equilibrium of PMA-SCD system is found to be extremely responsive to external chemical stimuli like temperature, pH, ionic strength of the medium, and organic solvent (DMSO) which projects them as potential platforms for various sensing application including Bio-analytes.
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Host-guest interaction of cytidine in β-cyclodextrin microcavity: Characterization and docking study
Samikannu Prabu,Samikannu Prabu,Krishnamoorthy Sivakumar,S. Kothai Nayaki,Rajaram Rajamohan,Rajaram Rajamohan +5 more
TL;DR: In this article, the formation of 1:1 a stoichiometry ratio of host-guest inclusion complex of Cytidine (CY) with a nano hydrophobic cavity of Beta-cyclodextrin (β-CD) in the solution phase is studied by a UV-visible spectrophotometer, fluorescence spectroscopy and time-resolved fluorescence.
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Biomaterials applications of cyclic polymers.
TL;DR: This review summarizes the applications of cyclic polymers in the field of biomaterials and highlights their potential in the biomedical field as well as addressing future challenges in this area.
References
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Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.