Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Recent advances in crosslinking chemistry of biomimetic poly(ethylene glycol) hydrogels
TL;DR: Recent progress in the crosslinking chemistries of biomimetic hydrogels with a special emphasis on hydrogel crosslinked from poly(ethylene glycol)-based macromers are reviewed.
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Nano-Assemblies of Modified Cyclodextrins and Their Complexes with Guest Molecules: Incorporation in Nanostructured Membranes and Amphiphile Nanoarchitectonics Design.
TL;DR: The supramolecular nanoarchitectures, which can be formed by amphiphilic cyclodextrin derivatives in mixtures with other molecules (phospholipids, surfactants, and olygonucleotides), are discussed.
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Cyclodextrin-based polymer materials: From controlled synthesis to applications
TL;DR: A review of CD-based polymers can be found in this paper, where the authors systematically discuss recent advances on the design, synthesis and characterization of CD based polymers, such as CD-cored star polymers and CD-threaded polymers.
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Self-assembly of supramolecularly engineered polymers and their biomedical applications.
Dali Wang,Gangsheng Tong,Ruijiao Dong,Yongfeng Zhou,Yongfeng Zhou,Jian Shen,Xinyuan Zhu,Xinyuan Zhu +7 more
TL;DR: The self-assembled supramolecular structures hold great potential as promising candidates in various biomedical fields, including bioimaging, drug delivery, gene transfection, protein delivery, regenerative medicine and tissue engineering.
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Complexation of phytochemicals with cyclodextrin derivatives - An insight.
TL;DR: It can be concluded that phytochemicals have multiple biological activities with broader safety index and improvement of their solubility will be truly beneficial to aid their effective delivery in healthcare.
References
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.