Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
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Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
TL;DR: This review focuses on various potential applications of supramolecular hydrogels as molecular biomaterials, classified by their applications in cell cultures, tissue engineering, cell behavior, imaging, and unique applications of hydrogelators.
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Biomedical Applications of Supramolecular Systems Based on Host-Guest Interactions.
Xing Ma,Yanli Zhao +1 more
TL;DR: Host−Guest Supramolecular Chemistry A 1.1.1: Aims to explore the role of “ghostly” particles in the determination of chiral stationary phases and their role in the “spatially modified” states.
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Hydrogels in a historical perspective: from simple networks to smart materials.
Sytze J. Buwalda,Kristel W. M. Boere,Pieter J. Dijkstra,Jan Feijen,Tina Vermonden,Wim E. Hennink +5 more
TL;DR: A historical overview of the developments in hydrogel research from simple networks to smart materials is provided to overcome several challenges to overcome for clinical translation.
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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.
Christopher B. Rodell,Sean P. Arlauckas,Michael F. Cuccarese,Christopher Garris,Ran Li,Maaz S. Ahmed,Rainer H. Kohler,Mikael J. Pittet,Ralph Weissleder +8 more
TL;DR: The ability of rationally engineered drug–nanoparticle combinations to efficiently modulate tumour-associated macrophages for cancer immunotherapy is demonstrated and R848, an agonist of the toll-like receptors TLR7 and TLR8 identified in a morphometric-based screen, is a potent driver of the M1 phenotype in vitro.
References
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Chaperone-like α-cyclodextrins assisted self-assembly of double hydrophilic block copolymers in aqueous medium
TL;DR: In this paper, a method in which α-cyclodextrins (α-CDs), "artificial chaperones", facilitate block copolymers self-assembling into the expected structure is presented.
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Well-defined core-shell nanoparticles containing cyclodextrin in the shell: A comprehensive study
Amani El Fagui,Florent Dalmas,Cédric Lorthioir,Véronique Wintgens,Gisèle Volet,Catherine Amiel +5 more
TL;DR: In this article, a hydrophobic poly (lactic acid) (PLA) core and a β-cyclodextrin polymer (Poly-β-CD) shell were used for drug delivery.
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Cyclodextrin Polymer Nanoassemblies: Strategies for Stability Improvement
TL;DR: The main goal of this work was to develop two strategies for stabilization of nanoassemblies made of β-cyclodextrin polymer and amphiphilic dextran associated through host-guest complexes, showing an improvement of shelf stability and resistance at relatively low concentrations of competitors.
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Sunflower‐Shaped Cyclodextrin‐Conjugated Poly(ε‐Lysine) Polyplex as a Controlled Intracellular Trafficking Device
Hak Soo Choi,Atsushi Yamashita,Tooru Ooya,Nobuhiko Yui,Hidetaka Akita,Kentaro Kogure,Rie Ito,Hideyoshi Harashima +7 more
TL;DR: Cyclodextrin containing polymers have been used as nonviral vectors due to their low cytotoxicity and their ability to modify the polyplex by inclusion complexation.
Journal Article
Cyclodextrins as sustained-release carriers
TL;DR: This review article describes the complexation of drug molecules with CDs to improve the properties of various formulations.