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Open AccessJournal ArticleDOI

Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.

Jianxiang Zhang, +1 more
- 01 Aug 2013 - 
- Vol. 65, Iss: 9, pp 1215-1233
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TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.
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This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.

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Citations
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Journal ArticleDOI

Anisotropic Amorphous X-ray Diffraction Attributed to the Orientation of Cyclodextrin.

TL;DR: The beauty of cyclic molecules is reflected in their host-guest complexation reactions, as well as their unique X-ray diffraction patterns, which suggest the possible use of rigidcyclic molecules as molecular orientation probes.
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Structural diversity in the host-guest complexes of the antifolate pemetrexed with native cyclodextrins: gas phase, solution and solid state studies.

TL;DR: The complexation of the antifolate pemetrexed (PTX) with native cyclodextrins was studied as a model for exploiting host–guest interactions of this class of guest molecules in the gas phase, in solution and in the solid state.
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Host-guest inclusion systems of mangiferin and polyamine-β-cyclodextrins: Preparation, characterization and anti-cancer activity

TL;DR: In this article, host-guest inclusion systems of mangiferin (MGF) with four polyamine-modified β-cyclodextrins (PAβCDs) have been characterized by 1D and 2D nuclear magnetic resonance (NMR), thermal gravimetric analysis (TGA), X-ray powder diffraction (XRD), and scanning electron microscopy.
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β-Cyclodextrin-capped ZnO-doped carbon dot as an advanced fluorescent probe for selective detection of dopamine

TL;DR: In this article, a one-pot synthesis strategy of water-soluble β-cyclodextrin-capped ZnO-doped carbon dot was proposed for selective and sensitive detection of dopamine (DA) in the presence of other interfering biomolecules.
References
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Journal ArticleDOI

Effect of pegylation on pharmaceuticals

TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Acidification of the endocytic and exocytic pathways

TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.
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