Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.
Jianxiang Zhang,Peter X. Ma +1 more
TLDR
This review focuses on state of the art and recent advances in the construction of cyclodextrin-based assemblies and their applications for controlled drug delivery and the future directions of this field are discussed.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2013-08-01 and is currently open access. It has received 673 citations till now.read more
Citations
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Gd(III) ion-chelated supramolecular assemblies composed of PGMA-based polycations for effective biomedical applications
TL;DR: A series of new poly(glycidyl methacrylate)-based supramolecular polycations with Gd3+ chelation were designed for low-toxicity and high-efficiency multifunctional gene delivery systems.
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Novel Water-Soluble Cyclodextrin-Based Conjugated Polymer for Selective Host-Guest Interactions of Cationic Surfactant CTAB and Reverse FRET with Rhodamine B Tagged Adamantyl Guest
Atul Kumar Dwivedi,Ravinder Singh,Ashutosh S. Singh,Kung-Hwa Wei,Chu Ya Wu,Ping Chiang Lyu,Hong-Cheu Lin +6 more
TL;DR: In this paper, a π-conjugated main-chain polymer P1 bearing a β-cyclodextrin (β-CD) pendant was designed and synthesized.
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Stimuliresponsive, auf Biomolekülen basierende Hydrogele und ihre Anwendungen
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Branched and ionic β-Cyclodextrins multilayer assembling onto polyacrylonitrile membranes for removal and controlled release of triclosan
Leyre Pérez-Álvarez,Janire Matas,F. Gómez-Galván,Leire Ruiz-Rubio,Luis Manuel León,José Luis Vilas-Vilela +5 more
TL;DR: The present study summarizes the formation and characterization of multilayers of polyacrylonitrile (PAN) membranes with β-cyclodextrin derivatives in order to be potentially interesting for triclosan (TR) controlled delivery with antibacterial purposes, as well as, for the removal of TR from wastewater.
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Merging supramolecular catalysis and aminocatalysis: amino-appended β-cyclodextrins (ACDs) as efficient and recyclable supramolecular catalysts for the synthesis of tetraketones
Yufeng Ren,Bo Yang,Xiali Liao +2 more
TL;DR: In this article, an amino-appended β-cyclodextrins (ACDs) with an amino side chain of different lengths at the primary face of β-CD were synthesized and employed in the catalytic synthesis of a series of tetraketones as supramolecular catalysts in water for the first time.
References
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.
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Complexation Thermodynamics of Cyclodextrins.
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Mark E. Davis,Jonathan E. Zuckerman,Chung Hang Jonathan Choi,David Seligson,Anthony W. Tolcher,Christopher A. Alabi,Christopher A. Alabi,Yun Yen,Jeremy D. Heidel,Antoni Ribas +9 more
TL;DR: Evidence is provided of inducing an RNAi mechanism of action in a human from the delivered siRNA and the presence of an mRNA fragment that demonstrates that siRNA-mediated mRNA cleavage occurs specifically at the site predicted for anRNAi mechanism from a patient who received the highest dose of the nanoparticles.
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Cyclodextrin Drug Carrier Systems.
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Acidification of the endocytic and exocytic pathways
TL;DR: The Exocytic Pathway and the CharacTERISTICS of PROTON ATPases are reviewed.